Oncology Probes

KREApureKREApure purification columns and platesKREApure purification columns and plates are based on a proprietarypurification matrix optimized for purifying ULS-labeled targetnucleic acids. The procedure quantitatively removes non-attachedlabel and provides optimal recovery of labeled nucleic acids.Unique features of the KREApure purification• Maximal removal of unreacted ULS-label• > 95% recovery of labeled nucleic acid• Efficient recovery of small fragmentsKREApure spin column purification.KREApure 96-well procedure.ReactionmixtureWash the column materialSpin for1 minuteUnreactedULSAdd ULS labeled materialSpin for1 minuteKREA purespin columnCollectiontubeSpin 1 minuteMax. speedBenchtop centrifugePurified,labeled targetCollect purified labeled materialYield comparison of different purification methods.100Cy3 ULS yields vs not purified7550Yields in %250KREApure Precipitation Silica column Gelfitration Size exclusionCy3 – ULS-labeled DNA has been purified using five different purification systems.Experiments were performed in triplicate.Ordering informationDescription Reactions Cat#KREApure columns 20 pcs KP-020KREApure columns 50 pcs KP-050KREApure 96* 1 plate KP-096* specific high-throughput labeling modules available upon requestKREApure111