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<strong>Cell</strong> Surface Adhesion MoleculesThree Major Classes• <strong>Cell</strong>-<strong>Cell</strong> Adhesion Molecules• CAMs (Ca 2+ Independent)• Cadherins (Ca 2+ Dependent)• Primarily Between Homologous <strong>Cell</strong>s• Signaling occurs• <strong>Cell</strong>-Substrate Molecules• Integrins• Bind to fibronectin, entactin, laminin, collagen• Bind the specific motif (RGD, arginine, glycine,aspratic)• Comprised <strong>of</strong> and unit
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