Antimicrobial Use Guidelines (AMUG) version 21 - UW Health

More documents

Recommendations

Info

14. Pichichiro ME. Use of selected cephalosporins in penicillin-allergic patients: aparadigm shift. Diag Micro Inf Dis 2007;57:13S-8S.15. Depestel DD, Benninger MS, Danzinger L, et al. Cephalosporin use in treatment ofpatients with penicillin allergies. J Am Pharm Assoc 2008;48:530-40.16. Kelkar PS, Li JTC. Cephalosporin allergy. NEJM 2001;345:804-9.17. Prescott WA, Kusmierski KA. Clinical importance of carbapenem hypersensitivity inpatients with self-reported and documented penicillin allergy. Pharmacotherapy2007;27:137-42.18. Prescott WA, DePestel DD, Ellis JJ, et al. Incidence of carbapenem-associatedallergic-type reactions among patients with versus patients without a reportedpenicillin allergy. CID 2004;38:1102-7.19. Sodhi M. Is it safe to use carbapenems in patients with a history of allergy topenicillin? JAC 2004;54:1155-7.20. Levitron I. Separating fact from fiction: the data behind the allergies and side effectscaused by penicillins, cephalosporins, and carbapenem antibiotics. CurrPharmaceutical Design 2003;9:983-8.21. Frumin J, Gallagher JC. Allergic cross-sensitivity between penicillin, carbapenem,and monobactam antibiotics: what are the chances? Ann Pharmacother2009;43:304-15.22. Strom BL, Schinnar R, Apter AJ, et al. Absence of cross-reactivity betweensulfonamide antibiotics and sulfonamide nonantibiotics. NEJM 2003;349:1625-35.
Order for beta-lactam antibioticPenicillin allergy?NoYesImplementorderYesNoPatient received anantibiotic in that classin the past withoutreaction?May try gradedchallenge if unsureType of reaction?Patient and/orfamily do notknow/recallreactionNon-severe, non-IgEmediated reactionDelayed maculopapular rashItchingGI intoleranceSevere, non-IgE mediatedreactionHemolysisStevens Johnson SyndromeToxic epidural necrolysisIgE mediated(type 1 reaction)Urticaria (hives)AngioedemaAnaphylaxisContact prescriber to usealternative agentContact prescriber to:1) Use alternative agent2) Do penicillin skin test3) Do graded challenge if felt tobe low risk of cross-reactivity
Page 2 and 3:
PREFACEThe Antimicrobial Use Guidel
Page 4 and 5:
Antimicrobial Cost Table (Cost info
Page 6 and 7:
Summary of Antibiotic Order Form: S
Page 8:
LUNGS/PULMONARYCommunity-Acquired P
Page 12 and 13:
PART I: BY DRUGABACAVIRFor up-to-da
Page 14 and 15:
constructed systemic-pulmonary shun
Page 16 and 17:
AMPICILLIN/SULBACTAM (Unasyn ® )Us
Page 18 and 19:
ATOVAQUONE/PROGUANIL (Malarone ® )
Page 20 and 21:
CEFAZOLINUsual DoseAdult: Moderate/
Page 22 and 23:
CommentsDose adjustment required fo
Page 24 and 25:
1. Typhoid fever. (NOTE: Third-gene
Page 26 and 27:
-Dutasteride-Eltrombopag-Theophylli
Page 28 and 29:
CLINDAMYCINUsual DoseAdult: 600-900
Page 30 and 31:
DAPTOMYCINInfectious Disease approv
Page 32 and 33:
Concurrent administration with peni
Page 34 and 35:
• Cisapride (contraindicated) •
Page 36 and 37:
• Oral contraceptives/hormones -
Page 38 and 39:
Synergy in infective endocarditis a
Page 40 and 41:
• Colchicine • Indinavir • Ta
Page 42 and 43:
• Donepezil • Pioglitazone• D
Page 44 and 45:
with linezolid should be considered
Page 46 and 47:
4. Life-threatening Gram-negative i
Page 48 and 49:
MOXIFLOXACINLevofloxacin and moxifl
Page 50 and 51:
Indications1. Uncomplicated cystiti
Page 52 and 53:
CommentsDose adjustment required fo
Page 54 and 55:
PIPERACILLIN/TAZOBACTAM (Zosyn ® )
Page 56 and 57:
PRIMAQUINEUsual DoseAdult: Malaria
Page 58 and 59:
RIFABUTINUsual DoseAdult (150 mg ca
Page 60 and 61:
• Chloramphenicol • Leflunomide
Page 62 and 63:
SULFISOXAZOLENo longer available as
Page 64 and 65:
TICARCILLIN/CLAVULANATE (Timentin
Page 66 and 67: 2. Recurrent urinary tract infectio
Page 68 and 69: VANCOMYCINUsual DoseAdult: 1 g Q12H
Page 70 and 71: Careful monitoring of patients usin
Page 72 and 73: APPENDIX B: UWHC SURGICAL ANTIMICRO
Page 74 and 75: GI:Appendectomy 3Anaerobic organism
Page 76 and 77: VascularLIKELYPATHOGENS• ANTIMICR
Page 78 and 79: Cleanorthopedicprocedures(other)Sta
Page 80 and 81: APPENDIX C: THERAPY FOR TUBERCULOSI
Page 82 and 83: p-Aminosalicylic acid(PAS)Granules
Page 84 and 85: Appendix D: UNIVERSITY OF WISCONSIN
Page 86 and 87: Appendix E: UWHC Guidelines for the
Page 88 and 89: B. Antifungal Prophylaxis for BMT a
Page 90 and 91: D. Cost ComparisonDrugAmphotericin
Page 92 and 93: 17. Maertens J, Glasmacher A, Herbr
Page 94 and 95: 47. Courtney R, Wexler D, Radwanski
Page 96 and 97: 2.1.7 Patient is without placement
Page 98 and 99: Medications Approved for Parenteral
Page 100 and 101: APPENDIX G: Serum Drug Concentratio
Page 102 and 103: APPENDIX H: Guidelines for Monitori
Page 104 and 105: 1. Patients with large volumes of d
Page 106 and 107: 16. Tsuji B, Rybak MJ. The influenc
Page 108 and 109: APPENDIX I: Infectious Diseases App
Page 110 and 111: APPENDIX J: UWHC Guidelines For the
Page 112 and 113: with aztreonam and other beta-lacta
Page 114 and 115: D. Side Chains1.2.5. The prescriber
Page 118 and 119: Appendix KUWHC Guidelines for Cost-
Page 120 and 121: sulfa and can be prescribed topatie
Page 122 and 123: superinfection: amoxicillin 1 g PO
Page 124 and 125: 17. Smucny J, Fahey T, Becker L, Gl
Page 126 and 127: Appendix M: Guidelines for the Prop
Page 128 and 129: D. CategorizationPatients should be
Page 130 and 131: Empiric coverage for Enterococcus i
Page 132 and 133: H. Necrotizing PancreatitisThe publ
Page 134 and 135: Bone or JointEndocarditis 4Streptoc
Page 136 and 137: Candidemia or candidiasis 11Non-neu
Page 138 and 139: 11. Pappas PG, Kauffman CA, Andes D
Page 140 and 141: piperacillin/tazobactam. There were
Page 142 and 143: D. Dose of Antibiotic1. Piperacilli
Page 144 and 145: TNAVasopressinVoriconazoleMeropenem
Page 146 and 147: pretreatment with an H1-histamine b
Page 148 and 149: formal consult is not required, but
Page 150: K. References1.0 Bliziotis IA, Ples
show all

Antimicrobial Use Guidelines (AMUG) version 21 - UW Health

Create successful ePaper yourself

Delete template?

Save as template?