Antimicrobial Use Guidelines (AMUG) version 21 - UW Health

D. Cost ComparisonDrugAmphotericin BdeoxycholateAmphotericin BLiposomalAmphotericin Blipid complexAnidulafunginCaspofunginDose(70 kg patient)Cost per day1 mg/kg/day IV daily $13.545 mg/kg/day IV daily $423.155 mg/kg/day IV daily 253.65Load – 200 mg IVMaintenance – 100 mg IV dailyLoad – 70 mg IVMaintenance – 50 mg IV daily$347.86$173.93$338.72$326.00Micafungin100 mg IV daily$86.74150 mg IV daily$130.11FluconazoleLoad – 400 mg IV$5.37Maintenance – 200 mg IV daily $2.68Fluconazole 200 mg PO daily $0.14ItraconazoleLoad – 200 mg PO TID$33.24Maintenance – 200 mg PO BID $22.16Posaconazole 200 mg PO Q8h $82.28VoriconazoleLoad – 6 mg/kg IV Q12h x 2dosesMaintenance – 4 mg/kg IV Q12h$485.31$323.54Voriconazole 200 mg PO BID $82.74CommentsRequires ID SectionapprovalNonformulary;requires IDapprovalNonformulary:requires ID SectionapprovalNonformulary;requires ID SectionapprovalRequires ID SectionapprovalRequires ID Sectionapproval except foruse according tothe standardoperatingprocedures of theHematologySectionRequires ID SectionapprovalRequires ID Sectionapproval