INSTITUTUL NAÅ¢IONAL DE CERCETARE-DEZVOLTARE - ICECHIM

1 Bioresources and biomaterials - OStudies on Peptides and Free Amino Acids from Eupatoria cannabiumAdina-Elena Segneanu, Ioan Grozescu, Paula Sfirloaga, Raluca Pop,Paulina Vlazan, Ion Neda*National Institute for Research and Development in Electrochemistry and Condensed Matter,Romania, 300569 Timisoara, 1 Plautius Andronescu, Phone 0256-494413, Fax 0256-204698,Eupatoria cannabium (Fam. Asteraceae) a herb from Romanian spontaneous flora iswell known in traditional medicine for their therapeutical properties 1,2 .The major compounds are: resines, flavanone glycosides triterpenenes, saponides,sterols, and minerals 3-5 .In recent years there have been numerous researches on biological,immunomodulating and antioxidant activities of Eupatoria cannabium extracts but there arestill contradictions relative to this issue.The paper investigates bioactive compounds, especially free amino acids and peptidesfrom plant extract. The chromatographic (HPLC, GC-MS) studies correlated withspectroscopy methods (UV-Vis, FT-IR and MS) was conducted to identify the amino acidscomposition.References[1]. Y. Li, Y. L. Zhao, Y.P. Yang, X.L. Li, (2011), Biochemical Systematics and Ecology 39849–852;[2]. Onunogbo, C., Ohaeri, O.C., Eleazu C.O., Eleazu, K.C., (2012) E3 Journal of MedicalResearch Vol. 1(4). pp. 057-062;[3]. Stroescu, V., (1998). Pharmacological basis of medical practice, Ed. Medicala,Bucuresti.[4] Bujor, O., (2003), Ghidul plantclor medicinale şi aromatice de la A la Z/Bucureşti: EdituraFiat Lux.[5] Stanescu, U., Hanceanu, M., Miron, A., Aprostoaie, C., (2004). Plante medicinale de la Ala Z, monografii ale produselor de interes therapeutic. Vol. 1. Ed. Gr. T Popa. Iasi, 280-282.