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2010 BC Guide in Determining Fitness to Drive

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Chapter 12:Peripheral Vascular DiseasesBACKGROUND12.1 About peripheral vascular diseasesThe term peripheral vascular diseases (PVDs) refers <strong>to</strong> circula<strong>to</strong>ry disorders <strong>in</strong>volv<strong>in</strong>g any of theblood vessels outside the heart, e.g. arteries, ve<strong>in</strong>s, and lymphatics of the peripheral vasculature.The four subcategories of PVDs that have the greatest relevance for driv<strong>in</strong>g are: peripheral arterial disease aneurysms dissections, and deep-ve<strong>in</strong> thrombosis.Peripheral arterial diseasePeripheral arterial disease (PAD) is characterized by partial or complete failure of the arterialsystem <strong>to</strong> deliver oxygenated blood <strong>to</strong> peripheral tissue. Atherosclerosis is the primaryunderly<strong>in</strong>g cause of PAD. Other causes <strong>in</strong>clude thrombembolic, <strong>in</strong>flamma<strong>to</strong>ry, or aneurismaldisease. Although PAD can affect both upper and lower extremities, lower extremity<strong>in</strong>volvement is more common. A large majority (70% <strong>to</strong> 80%) of <strong>in</strong>dividuals with PAD areasymp<strong>to</strong>matic. For those <strong>in</strong>dividuals who are symp<strong>to</strong>matic, symp<strong>to</strong>ms can progress from<strong>in</strong>termittent claudication (pa<strong>in</strong> while walk<strong>in</strong>g) <strong>to</strong> rest/nocturnal pa<strong>in</strong>, <strong>to</strong> necrosis/gangrene. Only1% <strong>to</strong> 2%, however, progress <strong>to</strong> limb amputation with<strong>in</strong> 5 years of the orig<strong>in</strong>al diagnosis.AneurysmsAn aneurysm is def<strong>in</strong>ed as a localized abnormal dilation of an artery by 50% above the normalsize. Although an aneurysm can form on any blood vessel, abdom<strong>in</strong>al aortic aneurysms (AAA)are most common, with 90% occurr<strong>in</strong>g below the renal arteries. Others <strong>in</strong>clude those occurr<strong>in</strong>g<strong>in</strong> the thoracic aorta (ascend<strong>in</strong>g 5%; aortic arch 5%; descend<strong>in</strong>g 13%), those <strong>in</strong> the comb<strong>in</strong>edthoracic and abdom<strong>in</strong>al aorta (14%), and iliac aneurysms (isolated 1%: comb<strong>in</strong>ed abdom<strong>in</strong>al andiliac 13%).Aortic dissectionAortic dissection is a different disease <strong>to</strong> aortic aneurysm. Most dissections are <strong>in</strong> apparentlynormal aortas, are sudden and often present with collapse. Apart from some congenitalconditions which predispose <strong>to</strong> dissections e.g. Marfan’s, there is no way <strong>to</strong> predict an aorticdissection.112

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