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2010 BC Guide in Determining Fitness to Drive

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NSAIDs often are used <strong>in</strong> the treatment of mild <strong>to</strong> moderate pa<strong>in</strong>, and <strong>in</strong>flammation, and fever <strong>in</strong>both acute and chronic conditions, such as: rheuma<strong>to</strong>id arthritis and osteoarthritis gout metastatic bone pa<strong>in</strong> headaches and migra<strong>in</strong>es, and mild <strong>to</strong> moderate pa<strong>in</strong> due <strong>to</strong> <strong>in</strong>flammation and tissue <strong>in</strong>jury (e.g., pa<strong>in</strong> associated with <strong>to</strong>othextraction, root canal, sports <strong>in</strong>juries, etc.). menstrual pa<strong>in</strong>Sedatives and hypnoticsSedative and hypnotic drugs are central nervous system depressants. They are used <strong>to</strong> treatanxiety, <strong>in</strong>somnia, alcohol withdrawal, as muscle relaxants, and anticonvulsants. The majorcategories are barbiturates, benzodiazep<strong>in</strong>es and a new class of non-benzodiazep<strong>in</strong>e sedativescalled Z drugs.Benzodiazep<strong>in</strong>es can be divided <strong>in</strong><strong>to</strong> short-act<strong>in</strong>g with a short half-life (less than 12 hrs), whichgenerally are used <strong>to</strong> treat <strong>in</strong>somnia, <strong>in</strong>termediate-act<strong>in</strong>g with a half-life (12 <strong>to</strong> 24 hrs), and longact<strong>in</strong>gwith a long half-life (more than 24 hrs), which are used <strong>to</strong> treat anxiety.Categories of sedatives and hypnotics, with examples of drugs <strong>in</strong> each category, are provided <strong>in</strong>the table below.Category Generic Name Brand NameBarbiturates phenobarbital various genericsalprazolamXanaxBenzodiazep<strong>in</strong>es with a short half-life triazolamHalcion®oxazepamSerax®Benzodiazep<strong>in</strong>es with an <strong>in</strong>termediatelorazepamAtivan®half-lifetemazepamRes<strong>to</strong>ril®clordiazepoxide Librium®clonazepamRivotrilBenzodiazep<strong>in</strong>es with a long half-lifediazepamValium®clorazepateTranxene®flurazepamDalmaneZ drugs (non-benzodiazep<strong>in</strong>es)zopicloneImovane®zolpidemSubl<strong>in</strong>ox356

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