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2010 BC Guide in Determining Fitness to Drive

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Non-steroidal anti-<strong>in</strong>flamma<strong>to</strong>riesNSAIDs are among the most commonly used pharmacological agents, with 10 millionprescriptions dispensed annually <strong>in</strong> Canada. The use of NSAIDs is predicted <strong>to</strong> <strong>in</strong>crease with theag<strong>in</strong>g population due <strong>to</strong> the association between age and musculoskeletal disorders such asosteoarthritis and rheuma<strong>to</strong>id arthritis.Sedatives and hypnoticsData from 2002 Canadian Community Health Survey <strong>in</strong>dicated that the percentage of those whohad used a sedative or hypnotic <strong>in</strong>creased with age, mov<strong>in</strong>g from 3.1% of the general population15 years and older, <strong>to</strong> 11.1% for those 75 and older. Overall, 7.2% of those with anxietydisorders had taken a sedative-hypnotic over the two days preced<strong>in</strong>g the survey.Benzodiazep<strong>in</strong>e use made up most of the sedative-hypnotic use <strong>in</strong> all analyzed demographic anddiagnostic groups. Information from this survey and other studies <strong>in</strong>dicate that benzodiazep<strong>in</strong>esare one of the most frequently used classes of drugs by seniors and women.Stimulants (for ADHD) and NarcolepsyNo data is available on the prevalence or <strong>in</strong>cidence of the use of stimulants as a treatment forADHD <strong>in</strong> Canada. An <strong>in</strong>dication of the use of stimulants for ADHD may be gleaned from theprevalence of the condition itself. Research <strong>in</strong>dicates that ADHD affects between 3% and 10%of children and between 4% and 6% of adults. Of adolescents and adults with ADHD, 76%achieve a therapeutic response with stimulant medication.29.3 Psychotropic drugs and adverse driv<strong>in</strong>g outcomesOpioidsResearch <strong>in</strong>dicates that the use of opioids can adversely affect driv<strong>in</strong>g performance, with thedegree of impairment dependent on the particular opioid used, dosage, previous use, developed<strong>to</strong>lerance, and time of day taken.AntidepressantsCurrently, there is little evidence <strong>to</strong> associate SSRIs or dual action agents with impaired driv<strong>in</strong>gperformance. Although limited, research <strong>in</strong>dicates that the use of tricyclic antidepressants isassociated with impairments <strong>in</strong> driv<strong>in</strong>g performance. This is evidenced by elevated crash rates,as well as measures of on-road performance and labora<strong>to</strong>ry tests of psychomo<strong>to</strong>r and cognitivefunction<strong>in</strong>g.358

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