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Adult Medical Emergency Handbook - Scottish Intensive Care Society

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long-term mortality, stroke, re-infarction, recurrent ischaemia and the<br />

need for coronary artery bypass graft (CABG) surgery as well as the<br />

combined end points of death or non-fatal re-infarction. This benefit<br />

is consistent across all patient subgroups and is independent of the<br />

thrombolytic agent used. The greatest benefit is seen in those patients<br />

treated within 12 hours of symptom onset.<br />

Patients with ST elevation acute coronary syndrome should<br />

be treated immediately with primary percutaneous coronary<br />

intervention.<br />

Patients undergoing primary percutaneous coronary intervention<br />

should be treated with a glycoprotein IIb/IIIa receptor antagonist.<br />

When primary percutaneous coronary intervention cannot<br />

be provided within 90 minutes of diagnosis, patients with ST<br />

elevation acute coronary syndrome should receive immediate<br />

thrombolytic therapy.<br />

adult medical emergencies handbook | NHS LOTHIAN: UNIVERSITY HOSPITALS DIVISION | 2009/11<br />

101

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