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Adult Medical Emergency Handbook - Scottish Intensive Care Society

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Table 3: Drugs that may be required in the management of Acute<br />

Transfusion Reactions<br />

RELEVANT<br />

EFFECTS<br />

DRUGS & DOSES NOTES<br />

Name Route & Dosage<br />

Oxygen 60-100% 1st line<br />

Bronchodilator Adrenaline 500 micrograms 1st line<br />

Vasopressor im repeated after<br />

5 mins if no<br />

better, or worse<br />

Expand blood 0.9% - If patient 1st line<br />

volume Saline, hypotensive,<br />

Gelofusine 20ml/kg over<br />

5 minutes<br />

Reduce fever Paracetamol Oral or rectal 2nd line<br />

and inflamm- 10 mg/kg Avoid aspirin<br />

atory response containing<br />

products if<br />

patient has low<br />

platelet count<br />

Inhibits Chlorphen- IV 0.1 mg/kg 2nd line<br />

histamine amine<br />

mediated (Chlorphenresponses<br />

iramine)<br />

Inhibits Salbutamol By 5mg nebuliser 2nd immune<br />

line<br />

mediated Amino- Use under<br />

bronchospasm phyllline expert guidance<br />

Vasopressor Adrenaline 5-10ml/hr Use only under<br />

Bronchodilator 6mg in 100ml<br />

5% dextrose<br />

(6%)<br />

expert guidance<br />

66 adult medical emergencies handbook | NHS LOTHIAN: UNIVERSITY HOSPITALS DIVISION | 2009/11

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