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Adult Medical Emergency Handbook - Scottish Intensive Care Society

Adult Medical Emergency Handbook - Scottish Intensive Care Society

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INTRAVENOUS INSULIN SLIDING SCALE REGIMEN<br />

Remember, intravenous insulin has a half-life of only 2.5<br />

minutes, so if intravenous insulin is disconnected for any<br />

appreciable length of time, hyperglycaemia will quickly ensue<br />

(unless subcutaneous insulin has been given).<br />

The insulin infusion is prepared by adding 50 Units of Actrapid insulin<br />

to 0.9% saline in a syringe to a total volume of 50ml. Thus, 1ml of the<br />

solution contains 1 unit of insulin. The doses of insulin are adjusted<br />

according to a sliding scale, which is prescribed as below.<br />

BG (mmol/l) Insulin infusion (Units actrapid/hour = ml/hour)<br />

>16 6 (test urine for ketones, call Dr as the sliding<br />

scale may need revision)<br />

13-15.9 4<br />

10-12.9 3<br />

7.0-9.9 2<br />

5.0-6.9 1<br />

4.0-4.9 0.5<br />

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