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JUEVES / THURSDAY<br />

120<br />

11.15 - 12.00 h<br />

CADERA / HIP<br />

Infecciones / Infections<br />

Moderador: Xavier Flores<br />

THE DIAGNOSIS AND MANAGEMENT OF<br />

PERI-PROSTHETIC INFECTIONS<br />

P McLardy-Smith, B Atkins, H Pandit, T Berendt, N<br />

Athanasou & the Oxford Hip and Knee Group (Richie<br />

Gill, David Beard, Vicky Flanagan, Chris Dodd, Max<br />

Gibbons, Roger Gundle, David Murray, Andrew Price,<br />

Duncan Whitwell)<br />

California (USA)<br />

Total hip replacement is probably the most successful operation<br />

ever devised and other joints, particularly the knee<br />

are now being successfully replaced. However peri-prosthetic<br />

infection remains a potentially catastrophic complication.<br />

Infection rates are reported at between 1- 2% and the risk<br />

of a peri-prosthetic infection runs over the entire life time of<br />

the joint. Peri-prosthetic infections can usefully categorised<br />

as early acute or chronic and late acute or chronic. The<br />

diagnosis of chronic infections, particularly late ones, may<br />

be difficult to achieve pre-operatively. Imaging techniques<br />

and serological testing can be useful but are not as yet<br />

reliable or specific. Aspiration or closed biopsy are similarly<br />

unreliable. Any joint revised for any reason may have an<br />

underlying infection. In a prospective study of 334 consecutive<br />

hip and knee revisions we sent multiple samples from each<br />

case for bacteriological and histological analysis. We used<br />

the histological appearance as the criterion for defining<br />

infection. By this definition 15% of infected cases were culture<br />

negative and one positive culture specimen has no predictive<br />

value for under lying infection. Two or more positive cultures<br />

out of 5 or 6 samples as a useful predictive value.<br />

In acute infections, if the components are soundly fixed,<br />

salvage should be attempted with adequate debridement<br />

sampling and lavage of the joint. Arthroscopic washout in<br />

Staphylococcal knee infections has a very poor outcome.<br />

We would then recommend long term antibiotic therapy.<br />

Salvage maybe possible in chronic infections, but usually<br />

the components are loose within the bone and a full revision<br />

will be required. Frozen section histological analysis of the<br />

tissue at the time of surgery can differentiate septic from<br />

aseptic loosening and maybe relied upon to choose between<br />

a one or a two stage revision.<br />

INFECTED TOTAL HIP ARTHROPLASTY.<br />

ONE STAGE REVISION<br />

B. M. Wroblewski, H. Nagai, P. D. Siney, P. A. Fleming<br />

The John Charnley Research Institute, Wrightington Hospital,<br />

Hall Lane, Appley Bridge Near Wigan (Great Britain)<br />

One of the most serious complications of THA is deep infection.<br />

Charnley realised the problem. This led to the development<br />

of clean air enclosure, total body exhaust suits and the introduction<br />

of the instrument tray system. Subsequently antibiotics<br />

were used both systematically and also as an addition to the<br />

acrylic cement. Occasional deep infection requires further intervention,<br />

either by removing the implant, or performing one<br />

or two stage revision.<br />

It has been the senior author’s practice to undertake one-stage<br />

revision provided the bone stock was of sufficiently good quality<br />

to ensure reasonable quality of component fixation. The technique<br />

is based on the accepted principle of infection management:<br />

Removal of all foreign body material and infected tissues,<br />

application of local antiseptics/antibiotics, closure of cavities,<br />

ensuring stability, drainage, rest, continuation of antibiotics.<br />

Between January 1974 and December 2001, 185 one-stage<br />

revisions were carried out by the senior author: 162 had a<br />

minimum follow-up of 5 years with a mean of 12.3 years (5.1<br />

– 27.6 years). 138 cases (85.2%) were free from infection.<br />

Presence of a sinus at revision did not affect the outcome<br />

adversely – on the contrary - 90.4% were infection free as<br />

compared with 82.7% of those without a sinus.<br />

THE MARSA GHOST<br />

Thorsten Gehrke<br />

Endo-Klinik. Hamburg (Alemania)

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