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MARTES / TUESDAY<br />

26<br />

interlock between implant and bone. The European designs<br />

had instead a roughened surface produced on a titanium<br />

alloy stem by “corundum blasting” the surface to a specific<br />

roughness but with out a specific porous coating. This<br />

treatment was expected to provide a surface onto which<br />

bone could grow to provide for long-term, secondary stability.<br />

There have been reports in the literature of successes with<br />

the Zweymüller and Spotorno (CLS) prostheses. With now<br />

more than 1,000,000 of these types of stems in place world<br />

wide, the clinical success of these tapered, wedge shaped<br />

prostheses suggests that this European philosophy is one<br />

that will continue into the decades to come. Survivorships in<br />

excess of 95% at as long as 20 years have been reported with<br />

no indication on radiograph of impending failure on the horizon.<br />

The results of these prostheses, coupled with the good results<br />

obtained with the AML type prostheses, suggest that<br />

we look at the similarities of the implants to discern the requirements<br />

for obtaining fixation of a femoral stem. The stages<br />

of fixation can be summarized as primary fixation, intermediate<br />

fixation and secondary fixation.<br />

- Primary fixation is that obtained in the operating room<br />

by driving a slightly oversized or wedge shaped implant<br />

into the bone. The interference of the stem in the bone<br />

leads to high pressure at the implant-bone interface and<br />

a “press-fit”.<br />

- Intermediate fixation is the means by which the implant<br />

remains stable while bone attaches itself to the implant<br />

for long-term stability.<br />

- Secondary fixation is that obtained by apposition of bone<br />

to a rough surface or apposition of bone to the surface<br />

and ingrowth into the depth of a porous coating. Interference<br />

probably disappears with bone remodeling and<br />

all long-term stability is from bone apposition to the surface<br />

of the implant.<br />

After secondary fixation is obtained the effects of bone loss<br />

through osteoporosis, fracture of the interface or debris or<br />

infection induced dissolution of the interface may cause an<br />

implant to become unstable in the bone. Continued postimplantation<br />

surveillance of implanted prostheses is imperative<br />

to determine the rate and potential solutions to late problems.<br />

Since different femoral components have similar results with<br />

respect to fixation, it is of more importance today to consider<br />

the functional restoration of a hip rather than the specifics of<br />

the stem. The surgeon should choose a stem with which he<br />

or she is comfortable and can reliably attain good primary<br />

fixation. Post operative care should take into account the<br />

shape and history of the stem so that the intermediate period<br />

can lead to osseointegration.<br />

In my practice, both porous coated and surface roughened<br />

implants have been successful in the long term. Having had<br />

to revise porous coated implants, particularly those that have<br />

achieved extensive ingrowth into porous coating in the diaphysis<br />

(such as the AML), I prefer the surface roughened alternative.<br />

REFERENCES<br />

Blaha JD: Pressfit Femoral Components in The Adult Hip Callahan<br />

JJ, Rosenberg AG and Rubash HE eds. 2nd ed. in press.<br />

BASIC SCIENCE OF HA-COATINGS<br />

Rudolph Geesink, MD PhD<br />

Professor of Orthopaedic Surgery, Maastricht University,<br />

Netherlands<br />

Cementless fixation of hip implants has evolved through<br />

several stages of evolution since the last decades. Results<br />

of mechanical presfit implantation resulted in lack of adequate<br />

long term fixation. Unavoidable increase in micro-motion between<br />

the stiff implant and the more flexible bone during<br />

loading through difference in elastic modulus of both components<br />

resulted in unacceptably high loosening rates. More<br />

rigid fixation would be required between implant and bone<br />

to withstand all forces during daily activities. Second generation<br />

fixation using porous-coatings using beads or meshes<br />

represented a significant step forward although the interface<br />

biology was far from ideal. Both experimental and autopsy<br />

retrieval studies confirmed that average ingrowth surface of<br />

porous-coated implants rarely exceeded 10 - 15 % of available<br />

ingrowth surface. In clinical practice this may be adequate<br />

to provide long term stability, however the reliability of the<br />

system to provide durable fixation can easily be impaired by<br />

adverse actions of the surgeon such as accidental undersizing,<br />

varus positioning or adverse patient parameters such as<br />

impaired bone quality as in osteoporosis, rheumatoid arthritis<br />

or otherwise. Substantial increase in ingrowth fixation potential<br />

of implants can be achieved by providing HA-coatings in<br />

implant surfaces. HA-coatings of good quality should have<br />

both adequate mechanical and biological properties.<br />

Main advantages of HA-coatings in clinical practice:<br />

- reduce the time for implant fixation & rehabilitation<br />

- minimize relative motion between bone and implant<br />

- allow more normal physiological stress transfer<br />

- encourage gap filling between implant and bone<br />

- seal periprosthetic access channels for fluid & particles<br />

Results of experimental studies by many authors confirm the<br />

superior behavior of HA-coatings to achieve these goals<br />

while autopsy retrieval studies confirm improved results in<br />

clinical practice for a great variety of patient populations, including<br />

rheumatoid arthritis patients, patients suffering from<br />

osteoporotic bone or other adverse phenomena.

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