Wellness Foods + Supplements 1/2022
Wellness Foods & Supplements is the first European magazine devoted exclusively to health ingredients, nutraceutical foods and beverages. Questions about the trade magazine Wellness Foods & Supplements? Interested in subscribing or advertising? The board of editors at Wellness Foods & Supplements kindly remains at your disposal.
Wellness Foods & Supplements is the first European magazine devoted exclusively to health ingredients, nutraceutical foods and beverages.
Questions about the trade magazine Wellness Foods & Supplements? Interested in subscribing or advertising? The board of editors at Wellness Foods & Supplements kindly remains at your disposal.
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AMD and micronutrients<br />
with AMD received either a dietary supplement<br />
with acetyl-L-carnitine, omega-3 fatty<br />
acids and coenzyme Q10 or a placebo. While<br />
the visual performance in the placebo group<br />
deteriorated significantly in the following 12<br />
months, the participants in the verum group<br />
showed a significant improvement in visual<br />
functions. (3)<br />
Acetyl-L-Carnitine<br />
Carnitine is formed from the amino acids<br />
lysine and methionine and plays an essential<br />
role in the transport of long-chain fatty<br />
acids into the mitochondria. In its acetylated<br />
form, carnitine can more easily cross cell<br />
membranes and act inside the cell. Acetyl-<br />
L-carnitine improves mitochondrial energy<br />
production and reduces lipofuscin deposition<br />
by promoting fat metabolism. In AMD,<br />
supplementation together with coenzyme<br />
Q10 and omega-3 fatty acids can significantly<br />
improve visual parameters and slow<br />
down disease progression. (3)<br />
Omega-3 fatty acids<br />
Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are<br />
polyunsaturated fatty acids that belong to the group of omega-3 fatty<br />
acids and form structural components of cell membranes. In the<br />
eye, high concentrations of DHA are stored in the outer segments of<br />
the photoreceptor cells. Omega-3 fatty acids have a beneficial effect<br />
on membrane fluidity and the function of membrane-associated<br />
proteins. This makes the membranes of the blood cells more flexible.<br />
They can pass through the narrow capillaries of our blood vessels<br />
more easily and improve tissue oxygenation. In AMD, supplementation<br />
with omega-3 fatty acids can significantly improve antioxidant<br />
capacity. A clinical study with 172 participants was also able to show<br />
a positive influence on the optical density of the macular pigment and<br />
a significantly beneficial effect on blood lipid levels. (4)<br />
Lutein<br />
The carotenoids lutein and zeaxanthin are stored in high concentrations<br />
in the macula. They filter out large portions of the high-energy<br />
blue-violet light and serve as “natural sunglasses” that mitigate the<br />
harmful effects of the radiation. With a reduced carotenoid content<br />
in the macula, there is both an increased harmful effect of the lipofuscin<br />
deposits and increased exposure to light, which particularly<br />
Expert in health ingredients and innovative formulations<br />
www.seanova.fr<br />
contact@seanova.fr +33(0)2 98 50 41 60<br />
//<br />
No. 1 April/May <strong>2022</strong><br />
29
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