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Medical Applications User Guide (pdf) - Freescale Semiconductor

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7.2<br />

Signal Acquisition<br />

This application is non-invasive because the<br />

optical sensor is composed of two LEDs<br />

that transmit light through the skin (finger<br />

or earlobe) to a photodiode. One LED is red<br />

with a wavelength of 660 nm and the other is<br />

infrared with a wavelength of 910 nm. The skin<br />

absorbs the light received by the photodiode.<br />

Each wavelength provides different data to<br />

calculate the percentage of hemoglobin.<br />

Deoxygenated and oxygenated hemoglobin<br />

absorb different wavelengths. Deoxygenated<br />

hemoglobin has absorption of around 660<br />

nm and oxygenated hemoglobin has higher<br />

absorption at 910 nm. These signals depend<br />

on the actual blood pressure, therefore the<br />

heart rate can also be measured.<br />

SaO2 as R<br />

R = log 10 (I ac ) λ1<br />

log10(I ac ) λ2<br />

Iac= Light intensity at λ1 or λ2, where only AC level<br />

is present λ1 or λ2 are the wavelengths used.<br />

7.3<br />

Circuit Design Overview<br />

This application starts with an optical<br />

sensor that is composed of two LEDs and<br />

a photodiode. The two LEDs have to be<br />

multiplexed to turn on. The photodiode detects<br />

when light is present by detecting current that<br />

is proportional to the intensity of the light,<br />

then the application uses a transimpedance<br />

amplifier to convert this current into voltage.<br />

Automatic gain control (AGC) controls the<br />

intensity of LEDs depending on each patient.<br />

A digital filter then extracts the DC component.<br />

The signal is passed to a digital band-pass<br />

filter (0.5 Hz–5 Hz) to get the AC component,<br />

then through a zero-crossing application to<br />

measure every heartbeat. Finally, this signal is<br />

passed as a voltage reference to the second<br />

differential amplifier to extract only the DC<br />

component and separate the AC and DC<br />

components. After this, the following ratio<br />

formula to obtain the oxygenated hemoglobin<br />

(SaO2) levels is used:<br />

R = [log (RMS value) x 660 nm] / [log (RMS<br />

value) x 940 nm]<br />

Home Portable <strong>Medical</strong><br />

Figure 7-1: Spectrum of Oxyhemoglobin and Deoxyhemoglobin<br />

Figure 7-1: Spectrum of Oxyhemoglobin and Deoxyhemoglobin<br />

Extinction Coeffiecient 10(RED)<br />

0.1<br />

freescale .com/medical 41<br />

600<br />

660 nm<br />

(INFRARED)<br />

940 nm<br />

700 800 900 1000<br />

Wavelength (nm)<br />

Figure 7-2: Pulse Oximetry Analog Interface<br />

Figure 7-2: Pulse Oximetry Analog Interface<br />

External<br />

LED and Driver<br />

Transimpedance<br />

Amplifier<br />

RBF<br />

(40 Hz-60 Hz)<br />

Display<br />

LED Red On/Off<br />

LED Red On/Off<br />

LED Red Brightness<br />

Infrared Brightness<br />

Photodiode<br />

Demultiplexer<br />

Hear Rate<br />

Monitor<br />

SaO 2<br />

Pseudo Analog<br />

Ground<br />

Differential<br />

Amplifier<br />

Zero<br />

Crossing<br />

LED Red and<br />

Infrared Sensors<br />

DAC_0<br />

DAC_1<br />

Digital Band<br />

Pass Filter<br />

HbO2<br />

Hb<br />

LED On/Off<br />

MCU Pins<br />

Select 0/1<br />

LED Range<br />

Control<br />

Multiplexer<br />

DC Tracking<br />

LPF (below<br />

0.5 Hz)<br />

Signal Conditioning<br />

AC Components<br />

ADC

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