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Presentation - University of Colorado Denver

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Unlike traditional Barker Hypothesis, this is not a case<br />

<strong>of</strong> nutrient mismatch – but instead more <strong>of</strong> a<br />

malaptation.<br />

Possible targets:<br />

• Lipid metabolic pathways:<br />

– Oxidation<br />

– Storage<br />

– Synthesis<br />

So… What’s the Program?<br />

• Inflammatory pathways<br />

– Priming <strong>of</strong> a pro-inflammatory state

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