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Presentation - University of Colorado Denver

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Juvenile<br />

Hypotheses<br />

1. Maternal high fat diet exposure will result in hepatic<br />

steatosis, inflammation and insulin resistance in<br />

juvenile <strong>of</strong>fspring at 1 yr <strong>of</strong> age.<br />

2. These metabolic abnormalities will be exacerbated<br />

when <strong>of</strong>fspring are fed a high fat diet after weaning<br />

to 1 yr <strong>of</strong> age.<br />

3. Mechanism may involve persistent activation <strong>of</strong><br />

inflammatory pathways in liver

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