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Presentation - University of Colorado Denver

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Benefits and Obstacles to<br />

working in NHP model<br />

• Longer gestation period<br />

(175d)<br />

• Similar Placentation<br />

• Organ development<br />

occurs in utero<br />

– pancreas, brain, adipose<br />

• Perform invasive studies<br />

that cannot be done in<br />

humans or fetal mice<br />

• Heterogenity<br />

• Free-living<br />

– Difficult to control<br />

food intake and<br />

exercise<br />

• Studies/data<br />

collection take a lot<br />

longer<br />

• Collaborative<br />

• Expensive<br />

• Heterogenity

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