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(12) PATENT APPLICATION PUBLICATION (21) Application No.1209/DELNP/2005 A<br />

(19) INDIA<br />

(22) Date <strong>of</strong> filing <strong>of</strong> Application :29/03/2005 (43) Publication Date : 16/03/2007<br />

(54) Title <strong>of</strong> <strong>the</strong> invention : "METHOD AND APPARATUS FOR MANIPULATING DROPLETS BY ELECTOWETTING-BASED TECHNIQUES<br />

(51) International classification :G01N 1/00 (71)Name <strong>of</strong> Applicant :<br />

(31) Priority Document No :10/253,342<br />

1)DUKE UNIVERSITY<br />

(32) Priority Date :24/09/2002<br />

Address <strong>of</strong> Applicant :OFFICE OF SCIENCE AND TECHNOLOGY,<br />

(33) Name <strong>of</strong> priority country :U.S.A.<br />

P.O.BOX 90083,DURHAM, NC 27708(US). U.S.A.<br />

(86) International Application No<br />

:PCT/US2003/012753 (72)Name <strong>of</strong> Inventor :<br />

Filing Date<br />

:24/04/2003<br />

1)PAMULIA, VAMSEE, K.<br />

(87) International Publication No :WO 2004/029585 2)POLLACK, MICHAEL, G.<br />

(61) Patent <strong>of</strong> Addition to Application Number :NA<br />

3)PAIK, PHILIP, Y.<br />

Filing Date<br />

:NA<br />

4)REN, HONG<br />

(62) Divisional to to Application Number<br />

:NA<br />

5)FAIR, RICHARD, B.<br />

Filing Date<br />

:NA<br />

No <strong>of</strong> Pages : 75 No <strong>of</strong> Claims : 85<br />

(57) Abstract :<br />

In a method for sampling a continuous liquid flow, <strong>the</strong> liquid flow is supplied to a surface along an input flow path. The liquid flow is sampled by forming a<br />

sample droplet from a portion <strong>of</strong> <strong>the</strong> liquid flow. The sample droplet is moved along an analysis flow path to a processing area <strong>of</strong> <strong>the</strong> surface, where <strong>the</strong><br />

sample droplet is processed. Discrete sample droplets are formed and moved using an electro wetting technique. A binary mixing apparatus and method are<br />

also provided. The apparatus comprises an array <strong>of</strong> electrodes, an electronic controller communicating with <strong>the</strong> electrodes, a sample droplet supply area<br />

communicating with <strong>the</strong> array, and an additive droplet supply area communicating with <strong>the</strong> array. The electronic controller alternately energizes and deenergizes<br />

selected electrodes to carry out droplet-to-droplet binary mixing operations to obtain one or more droplets having a target mixing ratio.<br />

The Patent Office Journal 16/03/2007 5710

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