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Image Reconstruction for 3D Lung Imaging - Department of Systems ...

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(a) TV solution at 8 th iteration<br />

(b) ℓ 2 solution at 8 th iteration<br />

Figure 7.11: <strong>Reconstruction</strong>s <strong>of</strong> Phantom B with 2.5% AWGN.<br />

Iteration 1<br />

(a)<br />

Iteration 4<br />

(d)<br />

TV<br />

phantom<br />

Iteration 2<br />

(b)<br />

Iteration 5<br />

(e)<br />

s15<br />

phantom<br />

Iteration 3<br />

(c)<br />

Iteration 6<br />

Figure 7.12: Pr<strong>of</strong>ile plots <strong>of</strong> the originating contrast and TV reconstructions <strong>for</strong> the phantom<br />

C, non-blocky, contrast. No Noise added. Pr<strong>of</strong>iles are vertical slices through the middle <strong>of</strong><br />

the reconstructed image.<br />

the results obtained from the 2D numerical experiments. This may be attributable to poor<br />

quality <strong>of</strong> the <strong>3D</strong> model in terms <strong>of</strong> number <strong>of</strong> mesh elements. More work is required in<br />

order to properly evaluate the per<strong>for</strong>mance <strong>of</strong> PD-IPM in <strong>3D</strong>.<br />

Aside on an Inverse Crime The act <strong>of</strong> employing the same model to generate, as well<br />

as to invert, simulated data is known as an inverse crime [122]. In earlier work [87] we have<br />

cautioned against unqualified publication <strong>of</strong> results obtained in this manner. The fact that<br />

an algorithm works with self simulated data does not imply that it will work well with real<br />

data because the use <strong>of</strong> self simulated data confers an advantage to the algorithm. The acid<br />

test <strong>for</strong> an algorithm occurs when it works successfully with empirical data. However, it<br />

is common methodology <strong>for</strong> researchers to start development <strong>of</strong> new algorithms using the<br />

same model <strong>for</strong> generation and subsequent inversion <strong>of</strong> simulated data. The justification is<br />

that an algorithm that does not work with such advantageous data will not work at all with<br />

real data. Once satisfactory results are obtained with the advantageous data, researchers<br />

111<br />

(f)

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