PCT/1998/22 - World Intellectual Property Organization

22/1998
4 Jun/juin 1998 PCT Gazette - Section I - Gazette du PCT 9757
(11) WO 98/23283 (13) A1
(21) PCT/US97/21421
(22) 25 Nov/nov 1997 (25.11.1997)
(25) en (26) en
(31) 08/755,713 (32) 25 Nov/nov 1996 (33) US
(25.11.1996)
(43) 4 Jun/juin 1998 (04.06.1998)
(51) 6 A61K 38/05, 31/215, C12Q 1/25, 1/68
(54) METHODS OF INHIBITING PROTEIN DEGRA-
DATION TO COMBAT MUSCLE WASTING
PROCEDES PERMETTANT D’INHIBER LA DE-
GRADATION DES PROTEINES POUR COM-
BATTRE LA FONTE MUSCULAIRE
(71) THE PRESIDENT AND FELLOWS OF HAR-
VARD COLLEGE [US/US]; Office of Patents,
Copyrights & Licensing, Harvard University, University
Place, Suite 256, 124 Mt. Auburn Street,
Cambridge, MA 02138 (US).
(for all designated States except / pour tous les États
désignés sauf US)
(72, 75) GOLDBERG, Alfred, L. [US/US]; 171 Crafts
Road, Brookline, MA 02167 (US). BHOITE–
SOLOMON, Vered [IL/US]; 104 Gerry Road,
Chestnut Hill, MA 02167 (US).
(74) IWANICKI, John, P.; Banner & Witcoff, Ltd.,
45th floor, One Financial Center, Boston, MA
02111 (US).
(81) AU CA JP US; EP (AT BE CH DE DK ES FI FR
GB GR IE IT LU MC NL PT SE).
Published / Publiée : (c)
(11) WO 98/23284 (13) A1
(21) PCT/US97/21451
(22) 21 Nov/nov 1997 (21.11.1997)
(25) en (26) en
(31) 60/052,525 (32) 27 Nov/nov 1996 (33) US
(27.11.1996)
(43) 4 Jun/juin 1998 (04.06.1998)
(51) 6 A61K 38/19, 38/00
(54) METHOD OF REGULATING NITRIC OXIDE
PRODUCTION
PROCEDE PERMETTANT DE REGULER LA
PRODUCTION DE MONOXYDE D’AZOTE
(71) IMMUNEX CORPORATION [US/US]; 51 University
Street, Seattle, WA 98101 (US).
(72) TROUTT, Anthony, B.; 3412 238th Street, S.W.,
Brier, WA 98036 (US).
(74) PERKINS, Patricia, Anne; Immunex Corporation,
51 University Street, Seattle, WA 98101 (US).
(81) AL AM AU BA BB BG BR CA CN CU CZ EE
GE HU IL IS JP KP KR LC LK LR LT LV MG
MK MN MX NO NZ PL RO SG SI SK SL TR TT
UA UZ VN YU; AP (GH KE LS MW SD SZ UG
ZW); EA (AM AZ BY KG KZ MD RU TJ TM);
EP(ATBECHDEDKESFIFRGBGRIEIT
LU MC NL PT SE); OA (BF BJ CF CG CI CM
GA GN ML MR NE SN TD TG).
(11) WO 98/23285
(21) PCT/GB97/03236
(13) A1
(22) 26 Nov/nov 1997 (26.11.1997)
(25) en (26) en
(31) 9624801.8 (32) 29 Nov/nov 1996
(29.11.1996)
(31) 9700900.5 (32) 17 Jan/jan 1997
(17.01.1997)
(33) GB
(33) GB
(43) 4 Jun/juin 1998 (04.06.1998)
(51) 6 A61K 38/21 // (A61K 38/21, 31:52)
(54) USE OF A COMBINATION OF PENCICLO-
VIR AND ALPHA–INTERFERON IN THE MA-
NUFACTURE OF A MEDICAMENT FOR THE
TREATMENT OF HEPATITIS B
UTILISATION D’UNE COMBINAISON DE
PENCICLOVIR ET D’ALPHA–INTERFERON
POUR PREPARER UN MEDICAMENT SER-
VANT A TRAITER L’HEPATITE B
(71) SMITHKLINE BEECHAM PLC [GB/GB]; New
Horizons Court, Brentford, Middlesex TW8 9EP
(GB).
(for all designated States except / pour tous les États
désignés sauf US)
(72, 75) BOON, Ronald, James [GB/GB]; SmithKline
Beecham Pharmaceuticals, New Frontiers
Science Park South, Third Avenue, Harlow, Essex
CM19 5AW (GB). ATKINSON, Gillian, Frances
[GB/GB]; SmithKline Beecham Pharmaceuticals,
New Frontiers Science Park South, Third Avenue,
Harlow, Essex CM19 5AW (GB).
(74) WATERS, David, Martin; SmithKline Beecham,
Corporate Intellectual Property, Two New Horizons
Court, Brentford, Middlesex TW8 9EP (GB).
(81) AL AM AT AU AZ BA BB BG BR BY CA CH
CN CU CZ DE DK EE ES FI GB GE GH HU ID
IL IS JP KE KG KP KR KZ LC LK LR LS LT
LU LV MD MG MK MN MW MX NO NZ PL PT
RO RU SD SE SG SI SK SL TJ TM TR TT UA
UG US UZ VN YU ZW; AP (GH KE LS MW SD
SZ UG ZW); EA (AM AZ BY KG KZ MD RU TJ
TM); EP (AT BE CH DE DK ES FI FR GB GR
IE IT LU MC NL PT SE); OA (BF BJ CF CG CI
CM GA GN ML MR NE SN TD TG).
Published / Publiée : (c)
(11) WO 98/23286 (13) A2
(21) PCT/IT97/00296
(22) 26 Nov/nov 1997 (26.11.1997)
(25) en (26) en
(31) RM96A000808 (32) 26 Nov/nov 1996 (33) IT
(26.11.1996)
(43) 4 Jun/juin 1998 (04.06.1998)
(51) 6 A61K 39/00, 51/00
(54) IMMUNOCONJUGATES COMPRISING HU-
MAN MONOCLONAL ANTIBODIES OR
FRAGMENTS THEREOF FOR DIAGNOSTIC
AND THERAPY
IMMUNOCONJUGUES COMPRENANT DES
ANTICORPS MONOCLONAUX HUMAINS
OU DES FRAGMENTS DE CES ANTICORPS,
UTILISES A DES FINS DIAGNOSTIQUES ET
THERAPEUTIQUES
(71) ISPROBI S.R.L. [IT/IT]; Viale Liegi, 44, I–00198
Roma (IT).
(for all designated States except / pour tous les États
désignés sauf US)
(71, 72) THALLER, Maria, Cristina [IT/IT]; Via Mario
Romagnoli, 12, I–00136 Roma (IT). BER-
LUTTI, Francesca [IT/IT]; Via Arno, 6, I–00198
Roma (IT). SELAN, Laura [IT/IT]; Via Peccioli,
51, I–00139 Roma (IT). SCHIPPA, Serena
[IT/IT]; Via Campo Catino, 54, I–00135 Roma
(IT). PASSARIELLO, Claudio [IT/IT]; Via Peccioli,
51, I–00139 Roma (IT). CRESTI, Stefania
[IT/IT]; Podere Vernina, 29, F–53020 S. Giovanni
d’Asso (IT). ROSSOLINI, Gian, Maria [IT/IT];
Via del Moro, 8, I–53100 Siena (IT). CATTANI,
Paola [IT/IT]; Via Raffaele Battistini, 21, I–00151
Roma (IT).
(72, 75) CATALANO, Carlo [IT/IT]; Viale Marconi,
903, I–00146 Roma (IT). PASSARIELLO,
Roberto [IT/IT]; Isprobi s.r.l., Viale Liegi, 44,
I–00198 Roma (IT).
(74) BANCHETTI, Marina et al. / etc.; Ing. Barzanò
& Zanardo Roma S.p.A., Via Piemonte, 26,
I–00187 Roma (IT).
(81) AL AM AT AU AZ BA BB BG BR BY CA CH
CN CU CZ DE DK EE ES FI GB GE GH HU ID
IL IS JP KE KG KP KR KZ LC LK LR LS LT
LU LV MD MG MK MN MW MX NO NZ PL PT
RO RU SD SE SG SI SK SL TJ TM TR TT UA
UG US UZ VN YU ZW; AP (GH KE LS MW SD
SZ UG ZW); EA (AM AZ BY KG KZ MD RU TJ
TM); EP (AT BE CH DE DK ES FI FR GB GR
IE IT LU MC NL PT SE); OA (BF BJ CF CG CI
CM GA GN ML MR NE SN TD TG).
(11) WO 98/23287 (13) A1
(21) PCT/US97/21661
(22) 25 Nov/nov 1997 (25.11.1997)
(25) en (26) en
(31) 08/756,014 (32) 25 Nov/nov 1996 (33) US
(25.11.1996)
(31) 60/045,030 (32) 28 Apr/avr 1997 (33) US
(28.04.1997)
(43) 4 Jun/juin 1998 (04.06.1998)
(51) 6 A61K 39/00, 38/00, 49/00, 47/36, 47/42, A01N
37/18, C07K 5/00, 14/00
(54) PEPTIDES WHICH MIMIC CANDIDA CARBO-
HYDRATE EPITOPES AND THEIR USE IN A
VACCINE
PEPTIDES IMITANT DES EPITOPES
D’HYDRATES DE CARBONE DE CANDIDA
ET LEUR UTILISATION DANS UN VACCIN
(71) THE RESEARCH AND DEVELOPMENT INS-
TITUTE, INC. [US/US]; Montana State University,
1171 West College, Bozeman, MT 59715
(US).
(for all designated States except / pour tous les États
désignés sauf US)
(72, 75) CUTLER, Jim, E. [US/US]; Montana
State University, Dept. of Microbiology, Lewis
Hall #109, Bozeman, MT 59717 (US). HAN,
Yongmoon [US/US]; Montana State University,
Dept. of Microbiology, Lewis Hall #109, Bozeman,
MT 59717 (US). GLEE, Pati [US/US];
Montana State University, Dept. of Microbiology,
Lewis Hall #109, Bozeman, MT 59717 (US).
(74) PRICE, Robert, L. et al. / etc.; Lowe Price
LeBlanc & Becker, Suite 300, 99 Canal Center
Plaza, Alexandria, VA 22314 (US).
(81) AU CA JP US; EP (AT BE CH DE DK ES FI FR
GB GR IE IT LU MC NL PT SE).
(11) WO 98/23288 (13) A1
(21) PCT/SE97/01928
(22) 18 Nov/nov 1997 (18.11.1997)
(25) en (26) en
(31) 9604322–9 (32) 25 Nov/nov 1996 (33) SE
(25.11.1996)
(43) 4 Jun/juin 1998 (04.06.1998)
(51) 6 A61K 39/106
(54) A VACCINE COMPOSITION COMPRISING HE-
LICOBACTER PYLORI FLAGELLIN POLYPEP-
TIDE
COMPOSITION DE VACCIN COMPRE-
NANT UN POLYPEPTIDE FLAGELLINE
D’HELICOBACTER PYLORI
(71) ASTRA AKTIEBOLAG [SE/SE]; S–151 85
Södertälje (SE).
(for all designated States except / pour tous les États
désignés sauf US)
(72, 75) BÖLIN, Ingrid [SE/SE]; Oljekvarnsgatan
13 A, S–414 65 Göteborg (SE). BERGLINDH,
Thomas [SE/SE]; Ripvägen 5, S–756 53 Uppsala
(SE). MELLGÅRD, Björn [SE/SE]; Olov
Skötkonungsgatan 7, S–412 66 Göteborg (SE).