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New Statistical Algorithms for the Analysis of Mass - FU Berlin, FB MI ...

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Figure 4.2.1: A monotonic<br />

relationship associated<br />

with a measuring<br />

process.<br />

68 CHAPTER 4. (BIO-)MEDICAL APPLICATIONS<br />

4.2 <strong>Statistical</strong> Remarks<br />

4.2.1 Measurement Fundamentals<br />

Campbell defines measurement as <strong>the</strong> “assignment <strong>of</strong> numerals to represent<br />

properties” (Campbell, 1920). This very general statement fits with <strong>the</strong> common<br />

perception <strong>of</strong> this term and is used in many different application domains:<br />

people are measuring <strong>the</strong> diameter <strong>of</strong> <strong>the</strong> sun, <strong>the</strong> mass <strong>of</strong> an electron, <strong>the</strong> intelligence<br />

<strong>of</strong> a human being, or <strong>the</strong> popularity <strong>of</strong> a television show. In o<strong>the</strong>r<br />

words, measurement is <strong>the</strong> objective representation <strong>of</strong> objects, processes, and<br />

phenomenon (Finkelstein and Leaning, 1984). Measurement captures in<strong>for</strong>mation<br />

about a system through its properties (also called characteristics, features,<br />

or attributes) which can be ei<strong>the</strong>r directly or indirectly observable. Additionally,<br />

<strong>the</strong>re exist relationships between <strong>the</strong> properties and <strong>the</strong> elements (i.e.<br />

measured representations) <strong>of</strong> a system. Thus, a system X is defined by <strong>the</strong><br />

properties xi chosen to represent it:<br />

X = (x1, x2, . . . , xi)<br />

Mostly, <strong>the</strong>re are three elements present: a property to be determined (P), a<br />

measured quantity (M) and a relationship between <strong>the</strong>se two quantities:<br />

M = f(P )<br />

Figure 4.2.1 is a graphical representation <strong>of</strong> <strong>the</strong> relationship associated with a<br />

measuring process.<br />

Since this <strong>for</strong>mulation only addressed <strong>the</strong> properties selected to represent<br />

<strong>the</strong> system one easily notices that, although being objective, it is an abstraction,<br />

and many important properties <strong>of</strong> <strong>the</strong> systems might not be included.<br />

Property selection is crucial since <strong>the</strong> validity <strong>of</strong> a system measurement is<br />

influenced by <strong>the</strong> number <strong>of</strong> properties used in <strong>the</strong> measurement. Clearly,<br />

properties affect <strong>the</strong> validity <strong>of</strong> a measure. There<strong>for</strong>e, <strong>for</strong>malized frameworks<br />

and <strong>the</strong>ories are required to clarify concepts about measurement within a particular<br />

domain.<br />

Obviously <strong>the</strong>re is a catch here with regard to property selection:<br />

In order to measure a system properly, one needs to know something<br />

about it - however, <strong>the</strong> main reason to measure a system is to gain an<br />

understanding <strong>of</strong> it. There<strong>for</strong>e, <strong>for</strong> most complex systems <strong>the</strong> properties<br />

that best define such a system are unknown, inaccessible, or only<br />

visible as an outcome. Measurement <strong>of</strong> <strong>the</strong>se systems requires use <strong>of</strong> a<br />

proxy or indirect measuring method which is essentially a model or approximation<br />

<strong>of</strong> <strong>the</strong> system property <strong>of</strong> interest. The process <strong>of</strong> deriving<br />

<strong>the</strong>se proxies usually involves reducing complex aspects <strong>of</strong> a system into<br />

understandable, measurable components.<br />

Having defined or selected <strong>the</strong> properties <strong>the</strong> subsequent measurement<br />

can be thought <strong>of</strong> as a process <strong>of</strong> assigning numbers (or generally<br />

symbols) to <strong>the</strong> properties <strong>of</strong> a system such that <strong>the</strong>se symbols reflect <strong>the</strong><br />

underlying relationships (or nature) <strong>of</strong> <strong>the</strong> properties (Caws, 1959).<br />

Having per<strong>for</strong>med <strong>the</strong> measurements one should analyze its main characteristics<br />

(Geisler, 2000), namely:

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