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Vol 6 - N° 2 - AIDA

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TRATTAMENTO DELLA<br />

LARVA MIGRANS<br />

CUTANEACON<br />

TIABENDAZOLO TOPICO<br />

arva mig rans cutanea (LMC), nota anche come "dermatite serpig inosa,<br />

eruzione strisciante, creeping eruption ", è una parassi tosi conseguente<br />

alla localizzazione nella cute di alcune specie di ne matodi (vermi rotondi)<br />

in stato larvale (Tab. 1).<br />

Tabella I : Agenti di Larva migrans cutanea<br />

Agenti eziologici più comuni<br />

- Ancylostoma braziliense<br />

- Ancylostoma ceylanicum<br />

- Ancylostoma caninum<br />

- Uncinaria stenocephala<br />

- Necator suillus<br />

- Bunostum phlebotum<br />

Agenti eziologici meno comuni<br />

- Ancylostoma duodenale<br />

- Necator americanus<br />

- Strongyloides (larva currens)<br />

- Strongyloides myopotami<br />

- Gnothostoma spinigerum<br />

SUMMARY<br />

Ospite<br />

cane,gatto<br />

cane, gatto, altri carnivori<br />

cane<br />

cane<br />

suino<br />

bovino<br />

uomo<br />

uomo<br />

uomo<br />

nutria<br />

cane,gatto<br />

Ospite<br />

Cutaneous larva migrans is a characteristic cutaneous eruption, usually named "creeping eruption" ,caused<br />

by filariform larvae of various nematode (hookworm).<br />

This disease is very common in many tropical or subtropical regions.<br />

Hookworks kive in the bowel of dogs and cats and their ova are deposited in the animals' faeces.The ova<br />

of these hookworms are deposited in the soil and haet into infective larvae, which then penetrate the<br />

human skin. Sandy, warm and shady areas are favorable. People who frequent beaches and farm workers<br />

are at increased risk.<br />

Within a few hous after penetration of the skin by a larva, an itching red papula develops. Migration is<br />

manifested by a serpiginous track with a severe pruritus that the patient suffers intolerably.<br />

Diagnosis is usually made on the basis of the clinical history and the appearance of the characteristic<br />

serpiginous track.<br />

We report four cases of cutaneous larva migrans, treated with tipical thiabendazone 10% in petrolatum<br />

applied twice a day for ten daus.<br />

Benzimidazoles by mouth are effective, but severe si de effects frequently occur so that this treatment is<br />

no longer recommended.<br />

We think that topical thiabendazole 10% in petrolatum is an effective terapeutic option with no side<br />

effects.<br />

43<br />

I<br />

o_AGGIORNAMENTI<br />

NCASI CLINICI<br />

VII Congresso<br />

<strong>AIDA</strong><br />

Canio Martinelli<br />

Marco Pozzi<br />

Francesco Leoncini<br />

U.O. Malattie infettive<br />

Azienda ospedaliera<br />

Careggi, Firenze<br />

Simonetta Giorgini<br />

Istituto di Clinica<br />

Dermosifilopatica,<br />

Università di Firenze<br />

Aurelio De Palma,<br />

Dermatologo<br />

Ambulatoriale<br />

ASL IO Firenze

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