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Appendix C Studies included in this review<br />

Thermal burns<br />

First Author and<br />

Year of Publication<br />

Brannen 1997 38<br />

Niezgoda 1997 39<br />

Hammarlund 1991 40<br />

Cianci 1990 41<br />

Gorman 1988 42<br />

Niu 1987 43<br />

Waisbren 1982 44<br />

Hart 1974 45<br />

NHMRC<br />

Level<br />

Study Design Location<br />

Dates of<br />

Enrolment Size<br />

II RCT USA ? ‡ 125 ?<br />

Characteristics of Study Population †<br />

Age (years)<br />

Mean (SD)<br />

II RCT USA ? 12 ? 7:5<br />

III-2 Comparative study Sweden ? 9 26 (24-29) § 9:0<br />

III-2 Comparative study USA<br />

III-3<br />

Comparative study<br />

with historical<br />

controls<br />

Australia<br />

Jan 1982 to<br />

Jul 1987<br />

T=Jul 1986<br />

to Jun 1988<br />

C=Jan 1983<br />

to Jun 1986<br />

Sex Ratio<br />

(M:F)<br />

I=50:12<br />

C=44:19<br />

<strong>Hyperbaric</strong> oxygen therapy 97<br />

21<br />

180<br />

III-2 Comparative study Taiwan After 1981 875<br />

III-2 Comparative study USA ? 72<br />

II RCT USA<br />

Nov 1972 to<br />

Jan 1974<br />

16<br />

I=28 (9)<br />

C=29 (8.3)<br />

I=34.2 (14.9)<br />

C=38.6 (17.2)<br />

I=27 (2-82) §<br />

C=26 (7/12-80)<br />

I=35.2 (15.0) #<br />

C=35.6 (14.8)<br />

I=21.62<br />

C=21.31<br />

* Abbreviations: C = comparison group, F = female, I = intervention group, M = male, RCT = randomised controlled trial, SD = standard<br />

deviation.<br />

† <strong>Information</strong> is given for intervention and comparison groups, if available. Otherwise, total study population values are stated.<br />

‡ Unstated, unclear, or unknown.<br />

§ Median of total population. Figures in parentheses are ranges.<br />

# Figures in parentheses are assumed to be standard deviations. Authors did not provide enough information for a definite conclusion.<br />

Diabetic wounds<br />

First Author and<br />

Year of Publication<br />

Faglia 1998 48<br />

Zamboni 1997 50<br />

Faglia 1996 47<br />

Doctor 1992 49<br />

Baroni 1987 46<br />

NHMRC<br />

Level<br />

Study Design Location<br />

III-2 Comparative study Italy<br />

III-2 Comparative study USA ? ‡<br />

II RCT Italy<br />

II RCT India<br />

III-2 Comparative study Italy<br />

Dates of<br />

Enrolment<br />

1990 to<br />

1993<br />

?<br />

?<br />

?<br />

?<br />

14:2<br />

Characteristics of Study Population †<br />

Siz<br />

e<br />

11<br />

5<br />

10<br />

Aug 1993 to<br />

Aug ’95 68<br />

2 years. No<br />

specific<br />

dates.<br />

30<br />

Jan 1982 to<br />

Dec 1984 28<br />

Age (years)<br />

Mean (SD)<br />

Sex Ratio<br />

(M:F)<br />

63.4 (9.9) 84:31<br />

I=63.6 (8.9)<br />

C=53.8 (7.8)<br />

I=61.7 (10.4)<br />

C=65.6 (9.1)<br />

I=56.2 (45-70) §<br />

C=59.8 (48-70)<br />

I=57.7 (7.4)<br />

C=59.4 (7.6)<br />

I=4:1<br />

C=4:1<br />

I=27:8<br />

C=21:12<br />

I=3:1<br />

C=2:1<br />

I=11:7<br />

C=6:4<br />

* Abbreviations: C = comparison group, F = female, I = intervention group, M = male, RCT = randomised controlled trial, SD = standard<br />

deviation.<br />

† <strong>Information</strong> is given for treatment and control groups, if available. Otherwise, total study population values are stated.<br />

‡ Unstated, unclear, or unknown.<br />

§ Figures in parentheses are ranges.

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