Source: Landcare Research (1964). Control of poisons. Royal ...

1080 Reassessment Application October 2006
Appendix C
indirectly indicate that all these tumor tissue possess aconitase activity. However, of all the neoplasms
studied, adenocarcinoma 755 can efficiently convert fluoroacetate to fluorocitrate as measured by citric
acid accumulation in the fluoroacetate poisoned tumor homogenates.
Dilks, P. and Lawrence, B. (2000). The use of poison eggs for the control of stoats. New Zealand journal of
zoology 27.
Keywords: poison/stoats/1080/lethal dose/field efficacy
Abstract: Stoats (Mustela erminea) are an important predator of many forest bird species in New Zealand,
and more effective methods for their control are being sought. Stoat control using Fenn traps has been
shown to prevent predation on mohua (Mohoua ochrocephala), but this technique is labour-intensive and
costly to use for protection of large areas of habitat. We evaluated 1080 delivered in eggs as a poison for
control of stoats. The lethal dose has been determined by captive and field trials, but attempts to implement
a large-scale control operation have given inconclusive results. To clarify the effectiveness of 1080 eggs as
a control technique, we carried out further field trials with radio-tagged stoats in the Makarora Valley.
Twenty animals were monitored by radio tracking, and data loggers and video cameras recorded their visits
to bait stations. The precise time an individual stoat ate a poison egg could be determined from data logger
and video information, and its fate was followed. Sixteen of twenty stoats were killed by 1080 eggs, three
died of other causes and one remained alive at the end of the trials.
Dobereiner, J. and Tokarnia, C. H. (1959). Poisoning of cattle by "erva de rato" (Palicourea marcgravii St.
Hil.) in the Itapicuru Valley, Maranhao. Arq Institut Biol Anim 2, 83-91.
Keywords: poisoning/livestock/occurrence in nature
Douglas, G. W., Woodfield, B. R. G, and Tighe, F. G (1959). 1080 poison. A major weapon in rabbit
control. The Journal of Agriculture (Victoria) 279-327.
Keywords: 1080/poison
Abstract: In the past four years poisoning with 1080 (sodium fluoroacetate) has become well established as
a major method of rabbit destruction in Victoria.
Early in 1953, successful trials with 1080, using apple as bait, were carried out in the Jack River and
Yarram districts of Victoria. Kills were estimated to be between 90 and 99 per cent, of the rabbits in the
areas where the poisoning was effected, and further trials in the Yarram district confirmed these estimates.
Douglas, M. H. (1967). Control of thar (Hemitragus jemlahicus): evaluation of a poisoning technique. New
Zealand journal of science 10, 511-526.
Keywords: poisoning/1080/carrot/poison/secondary poisoning
Abstract: An attempt was made to evaluate a poisoning technique utilizing compound 1080 and carrots for
the control of thar. Pre-poisoning and post-poisoning counts were undertaken in three Zonesto define the
effectiveness of the poison and pre-feeding. Zone I with no pre-feeds had an estimated kill of 11%, Zone II
with one pre-feed an estimated kill of 30%, Zone III with two pre-feeds an estimated kill of 51%.
Supplementary results were collected on secondary poisoning, identification of 1080 death, whether
poisoning took a biased sample of the population, and biological data.
DuBois, K. P. (1948). New rodenticidal compounds. Journal of the American Pharmaceutical Association
37, 307-310.
Keywords: sodium fluoroacetate/fluoroacetate/efficacy/antidote/poisoning/lethal dose/rodents
Abstract: The toxicological and some of the pharmacological properties of Castrix, α-napthylthiourea, and
sodium fluoroacetate are reviewed. Information relating to the toxicity and rodenticidal efficacy of 2chloro-4-dimethylamino-6-methylpyrimidine
is reported. Sodium pentabarbital has been found to be
effective as an antidote for Castrix poisoning.
Dummel, R. J. and Kun, E. (1969). Studies with specific enzyme inhibitors. The Journal of Biological
Chemistry 244, 2956-2969.
Keywords: chemistry/enzyme/mode of action/analysis/fluorocitrate
Abstract: Isolation of D and L isomers of erythro-fluorocitric acid was accomplished by first separation of
diastereomeric racemates as cyclohexamine salts of diethyl fluorocitrate. This was followed by resolution
44