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A Current Bibliography on African Affairs - Baywood Publishing

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426 / A CURRENT BIBLIOGRAPHY ON AFRICAN AFFAIRS<br />

PSYCHOLOGICAL STUDIES<br />

1437. Adewuya, A. O. et al. RELATIONSHIP BETWEEN DEPRESSION AND<br />

QUALITY OF LIFE IN PERSONS WITH HIV INFECTION IN NIGERIA. Internati<strong>on</strong>al<br />

Journal of Psychiatry in Medicine. 2008, 38(1):43-51.<br />

Despite the fact that two-thirds of all the people with HIV live in sub-Saharan Africa,<br />

little is known about the emoti<strong>on</strong>al state and quality of life (QOL) of subjects with HIV in<br />

this regi<strong>on</strong>. The objective of this study was to evaluate the associati<strong>on</strong> between clinical<br />

depressi<strong>on</strong> and quality of life in a group of HIV sero-positive subjects in Nigeria. Poorer<br />

health related QOL in Nigerian subjects with HIV was associated with depressi<strong>on</strong>, lower<br />

educati<strong>on</strong>al and socioec<strong>on</strong>omic levels, and poor social support. Early identificati<strong>on</strong> and<br />

referral of patients with depressi<strong>on</strong> needs to be incorporated into interventi<strong>on</strong> programs<br />

designed for HIV infected individuals in this regi<strong>on</strong>.<br />

1438. Boyer, P. et al. EFFICACY, SAFETY, AND TOLERABILITY OF FIXED-<br />

DOSE DESVENLAFAXINE 50 AND 100 MG/DAY FOR MAJOR DEPRESSIVE<br />

DISORDER IN A PLACEBO-CONTROLLED TRIAL. Internati<strong>on</strong>al Clinical Psychopharmacology.<br />

2008, 23(5):243-253.<br />

The objective of this study was to assess the efficacy, safety, and tolerability of<br />

desvenlafaxine (administered as desvenlafaxine succinate) 50 and 100 mg/day for major<br />

depressive disorder (MDD). Both doses of desvenlafaxine were generally well tolerated.<br />

The most comm<strong>on</strong> treatment-emergent adverse events were nausea, dizziness, insomnia,<br />

c<strong>on</strong>stipati<strong>on</strong>, fatigue, anxiety, and decreased appetite. Fixed doses of desvenlafaxine 50 and<br />

100 mg/day are safe, generally well tolerated, and effective at a clinically relevant level for<br />

the treatment of MDD.<br />

1439. Cluver, L. D., F. Gardner, and D. Operario. EFFECTS OF STIGMA ON THE<br />

MENTAL HEALTH OF ADOLESCENTS ORPHANED BY AIDS. Journal of Adolescent<br />

Health. 2008, 42(4):410-417.<br />

By 2010, an estimated 18.4 milli<strong>on</strong> children in Sub-Saharan Africa will be orphaned by<br />

AIDS. Research in South Africa shows that AIDS orphanhood is independently associated<br />

with heightened levels of psychological problems. This study is the first to explore the<br />

mediating effects of stigma and other factors operating <strong>on</strong> a community level, <strong>on</strong> associati<strong>on</strong>s<br />

between AIDS orphanhood and mental health. We assessed the associati<strong>on</strong>s of four<br />

risk factors that can potentially be addressed at a community level (bullying, stigma,<br />

community violence, and lack of positive activities) with psychological problems and<br />

orphanhood status. Multivariate analyses c<strong>on</strong>trolling for age and gender showed that<br />

experience of stigma significantly mediated associati<strong>on</strong>s between AIDS orphanhood and<br />

poor psychological outcomes. Reducti<strong>on</strong> of AIDS-related stigma could potentially reduce<br />

adverse psychological outcomes am<strong>on</strong>g AIDS-orphaned adolescents.<br />

1440. Crouch, R. B. A COMMUNITY-BASED STRESS MANAGEMENT PRO-<br />

GRAM FOR AN IMPOVERISHED POPULATION IN SOUTH AFRICA. Occupati<strong>on</strong>al<br />

Therapy Internati<strong>on</strong>al. 2008, 15(2):71-86.<br />

The development and evaluati<strong>on</strong> of a program for the effective management of stress in<br />

an impoverished rural community is the subject of this research study. A random sample of<br />

160 participants was selected from the rural populati<strong>on</strong> of the Limpopo Province of South

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