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Parasites and Biliary stones

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Endoscopic retrograde cholangiopancreatography ١٣١<br />

defined as the presence of melena, hematochezia, or hematemesis<br />

associated with a hemoglobin decrease of at least 2 g/dL or the need for<br />

blood transfusion (Freeman et al., 1996). The reported incidence of<br />

hemorrhage after sphincterotomy ranges from 0.76% to 2%. In roughly<br />

half of cases this bleeding is delayed (recognition 1 or more days after the<br />

examination) <strong>and</strong> can occur up to 1 to 2 weeks later. The risk of severe<br />

hemorrhage (i.e., requiring 2 or more units of blood, surgery, or<br />

angiography) is estimated to be 0.1% to 0.5% (Loperfido et al., 1998).<br />

Risk factors for hemorrhage include coagulopathy at the time of the<br />

examination, the use of anticoagulants within 72 hours of the<br />

sphincterotomy, the presence of acute cholangitis or papillary stenosis<br />

<strong>and</strong> the use of precut sphincterotomy, (Masci et al., 2001).<br />

Ways to prevent hemorrhage:<br />

Bleeding can mostly be avoided by correcting any coagulopathies,<br />

withholding anticoagulant medications for up to 3 days after a<br />

sphincterotomy <strong>and</strong> the use of alternating coagulating <strong>and</strong> cutting<br />

diathermy (Qaseem et al., 1996 <strong>and</strong> Tanaka, 2002).<br />

Catalano et al. (1995) suggested that prophylactic injection of the<br />

sphincterotomy site with epinephrine for endoscopically observed<br />

bleeding, or even a sclerosing agent in patients with coaglopathy, may<br />

reduce the risk of hemorrhage.<br />

ERCP-induced hemorrhage is monitored clinically <strong>and</strong> with<br />

laboratory tests (Baille, 1998), therefore, intraluminal bleeding is<br />

primarily recognized (Patel <strong>and</strong> Shaps, 1982). CT is not typically<br />

performed for diagnosis of hemorrhage; however, blood may be detected<br />

if CT is performed for another indication. CT findings of acute duodenal<br />

hemorrhage are duodenal wall thickening <strong>and</strong> a high-attenuation mass in

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