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Parasites and Biliary stones

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Treatment of calcular obstructive jaundice ٨٣<br />

of pigtail over straight stents for definitive treatment of CBDS is however<br />

limited (Hui et al., 2003).<br />

Extracorporeal shockwave lithotripsy:<br />

Extracorporeal shockwave lithotripsy (ESWL) was first used<br />

treating gall<strong>stones</strong> in 1980s following its successful use in fragmenting<br />

renal calculi (Sauerbruch et al., 1986). Shock waves are generated<br />

outside the body using electrohydraulic, electromagnetic shockwave<br />

systems. First generation lithotriptors required patients to be immersed in<br />

a water bath <strong>and</strong> often required general anaesthesia. Subsequent<br />

generation of lithotriptors do not require immersion in a water bath <strong>and</strong><br />

can be performed under intravenous sedation. Complete duct clearance of<br />

common bile duct <strong>stones</strong> following ESWL range between 83% <strong>and</strong> 93%.<br />

The majority of patients will require endoscopic extraction of the bile<br />

stone fragments following ESWL, although approximately 10% of <strong>stones</strong><br />

may subsequently pass spontaneously following treatment (Sackmann et<br />

al., 2001).<br />

Chemical dissolution therapy:<br />

Due to the side effects of the chemical used (diethyl ether), the<br />

procedure was not widely practiced. The discovery of mono-octanoin as a<br />

cholesterol stone dissolving agent, not also effective to remove CBDS<br />

(Palmer <strong>and</strong> Hofmann, 1986). The chemical is administered via a<br />

nasobiliary catheter, T-tube or percutaneous catheter <strong>and</strong> therapy is<br />

required for at least several weeks making therapy less practical. The use<br />

of methyl tertiary butyl ether (MTBE) has advantages over other<br />

chemical dissolution agents, mainly that of faster kinetics (Neoptolemos<br />

et al., 1990).

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