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Parasites and Biliary stones

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Abstract<br />

Gall stone disease remains one of the most common medical problems<br />

leading to surgical intervention. The risk factors predisposing to gallstone<br />

formation include obesity, diabetes mellitus, estrogen <strong>and</strong> pregnancy,<br />

hemolytic diseases, <strong>and</strong> cirrhosis . It is important to remember that<br />

gall<strong>stones</strong> can lead to a variety of other complications including<br />

choledocholithiasis. About 15% of patients with gall<strong>stones</strong> have<br />

choledocholithiasis. Stones in the common duct usually originate in the<br />

gallbladder but may also form de novo in the bile duct. Stones from gall<br />

bladder which migrate up to the intra-hepatic ducts leading to formation of<br />

Hepatolithiasis.<br />

Helminthic invasion of the human biliary tract is a prominent medical<br />

<strong>and</strong> surgical problem especially in tropical <strong>and</strong> subtropical areas where these<br />

parasites are endemic. Helminthic infestation may affect the liver <strong>and</strong>/or the<br />

biliary tract either during passage of worms through these structures or<br />

because these organs serve as their natural habitat. The parasitic infestations<br />

affecting the biliary tract including the nematode Ascaris lumbricoides, the<br />

trematodes Opisthorchis viverrini <strong>and</strong> felineus, Clonorchis sinensis,<br />

Dicrocoeliasis <strong>and</strong> Fasciola hepatica, <strong>and</strong> the cestodes Echinococcus<br />

granulosus <strong>and</strong> multilocularis, also some protozoa can cause biliary tract<br />

disease as Cryptosporidium, <strong>and</strong> Giardiasis.

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