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UCLA Graduate Catalog 1980-81 - Registrar - UCLA

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214 / MOLECULAR BIOLOGY<br />

the instructor . Fields of study may be in bacteriology,<br />

immunochemistry , immunogenetics, microbial<br />

genetics, mycology, parasitology, virology,<br />

viral oncology, tumor biology, or cell biology.<br />

Graded S/U. The Staff<br />

MOLECULAR BIOLOGY<br />

(INTERDEPARTMENTAL)<br />

(Molecular Biology<br />

Room 168)<br />

Institute Bldg.<br />

D.E. Atkinson , Ph.D., Professor of Chemistry.<br />

Marcel A. Baluda, Ph.D., Professor of Viral Oncology.<br />

Paul D. Boyer, Ph.D., Professor of Chemistry.<br />

William R. Clark, Ph.D., ProfessorofCell Biology.<br />

R. John Collier. Ph.D., Professor of Microbiology.<br />

David S. Eisenberg , Ph.D., Professor of Molecular Biology in<br />

Chemistry.<br />

F.A. Eiserling, Ph.D., Professor of Microbiology.<br />

John Fessler , Ph.D., Professor of Molecular Biology in Biology.<br />

C. Fred Fox, Ph.D., Professor of Molecular Biology in Microbiology.<br />

Dohn G. Glitz, Ph.D., Professor of Biological Chemistry.<br />

Issac M . Harary , Ph.D., Professor of Biological Chemistry.<br />

James A . Lake , Ph.D., Professor of Molecular Biology in Biology.<br />

George Laties, Ph.D., Professor of Plant Physiology.<br />

Donald P. Nierlich, Ph.D., Professor of Microbiology.<br />

George Popjak, Ph.D., Professor of Psychiatry and Biological<br />

Chemistry.<br />

Dan S. Ray, Ph.D., Professor of Molecular Biology in Biology.<br />

W.R. Romig, Ph.D., Professor of Microbiology.<br />

Winston A. Salser, Ph.D., Professor of Molecular Biology in<br />

Biology.<br />

Verne N. Schumaker, Ph.D., Professor of Molecular Biology in<br />

Chemistry.<br />

Larry Simpson, Ph.D., Professor of Cell Biology.<br />

Fritiof S. Sjostrand, Ph.D., Professor of Biology.<br />

Roberts A. Smith, Ph.D., Professor of Chemistry.<br />

Clara Szego, Ph.D., Professor of Biology.<br />

Philip Thornber , Ph.D., Professor of Molecular Biology in<br />

Biology.<br />

Randolph Wall, Ph.D., Professor of Microbiology and<br />

Immunology.<br />

Felix Wettstein , Ph.D., Professor of Molecular Biology in Microbiology<br />

and Immunology.<br />

Charles A. Wist, Ph.D., Professor of Chemistry.<br />

Irving Zabin, Ph.D., Professor of Biological Chemistry.<br />

Clifford Brunk, Ph.D., Associate Professor of Biology.<br />

George C. Fareed, Ph.D., Associate Professor of Molecular<br />

Biology in Microbiology and Immunology.<br />

Michael Grunstein, Ph.D., Associate Professor of Molecular<br />

Biology in Biology.<br />

Harvey Herschman. Ph.D., Associate Professor of Biological<br />

Chemistry.<br />

Bruce Howard, Ph.D., Associate Professor of Biological Chemistry.<br />

John M . Jordan, Ph.D., Associate Professor of Molecular Biology<br />

in Chemistry.<br />

Harumi Kasamatsu, Ph.D., Associate Professor of Molecular<br />

Biology in Biology.<br />

David S. Sigman, Ph.D., Associate Professor of Biological<br />

Chemistry.<br />

William T. Wickner , Ph.D., Associate Professor of Molecular<br />

Biology in Biological Chemistry.<br />

Gary Wilcox, Ph.D., A ssociate Professor of Microbiology.<br />

Patrice Zamenhof, Ph.D., Associate Professor of Biological<br />

Chemistry.<br />

Arnold J. Berk , Ph.D., Assistant Professor of Microbiology.<br />

Steven G. Clarke, Ph.D., Assistant Professor of Chemistry.<br />

Jay Gralla, Ph.D., Assistant Professor of Molecular Biology in<br />

Chemistry.<br />

Judith Lengyel, Ph.D., Assistant Professor of Molecular Biology<br />

in Biology.<br />

Harold B. Martinson, Ph.D., Assistant Professor of Chemistry.<br />

Emil Reisler, Ph.D., Assistant Professor of Molecular Biology in<br />

Chemistry.<br />

Robert M. Sweet, Ph.D., Assistant Professor of Molecular<br />

Biology in Chemistry.<br />

Allan J. Tobin, Ph.D., Assistant Professor of Biology.<br />

Richard L. Weiss, Ph.D., Assistant Professor of Chemistry.<br />

Bernadine Wisnieski, Ph.D., Assistant Professor of Microbiology.<br />

Owen N. Witte, Ph.D., Assistant Professor of Microbiology.<br />

The Ph.D. Degree<br />

The Ph. D. degree program in Molecular Biology is<br />

offered under the supervision of an interdepart-<br />

mental committee . The Molecular Biology Institute<br />

serves this committee and the various departments<br />

concerned in support of faculty research and teaching<br />

associated with the Ph.D. program. Staff members<br />

are drawn from participating departments and<br />

from the Molecular Biology Institute. Areas for<br />

study include structure and function of<br />

macromolecules, molecular genetics and virology;<br />

bioenergetics, catalysis and control; molecular basis<br />

of cellular architecture, development and evolution<br />

; neurobiology<br />

cancer and its control.<br />

and the molecular basis of<br />

Admission Requirements . In general, recommended<br />

undergraduate training for the Ph.D.<br />

degree program includes a major in a biological or<br />

physical science. Coursework should include mathematics<br />

through calculus, one year each of general<br />

and of organic chemistry, one year each of physics<br />

and physical chemistry based on the use of<br />

calculus, and one year of biology. Undergraduate<br />

requirements may be modified for qualified candidates<br />

with interests in certain areas . Candidates<br />

who enter the program with course deficiencies<br />

will be expected to fulfill<br />

program.<br />

these early in the graduate<br />

Only superior students are admitted, and in addition<br />

to the application, transcripts and statement of<br />

purpose, three letters of recommendation are<br />

required along with <strong>Graduate</strong> Record Examination<br />

(GRE) scores. There are no special application<br />

forms, but copies of materials sent to <strong>Graduate</strong><br />

Admissions Office should also be sent directly to<br />

MBI.<br />

Address for information: <strong>Graduate</strong> Office, Molecular<br />

Biology Institute , <strong>UCLA</strong>, Los Angeles, CA 90024.<br />

Advising . <strong>Graduate</strong> Adviser: Dr. John H. Fessler<br />

Upon entering, a provisional advisory committee of<br />

three faculty members is appointed. After completing<br />

three one-quarter rotations, the student may<br />

choose a permanent Ph.D. adviser. In the initial<br />

year, there is a quarterly review by the Advisory<br />

Committee. The Ph.D. committee makes an overall<br />

assessment<br />

adviser.<br />

on the basis of annual reports from the<br />

Admission to the Doctoral Program . In addition to<br />

University requirements, six quarters of the M298<br />

laboratory work are required.<br />

Foreign Language Requirement . There is no<br />

foreign language requirement for the Ph.D. degree.<br />

Course Requirements . The usual program is two<br />

regular courses per quarter or the equivalent of<br />

eight quarter units of upper division or graduate<br />

work. Six quarters M298, Seminar in Current<br />

Topics in Molecular Biology, are required.<br />

Written and Oral Qualifying Examinations.<br />

Examinations will be given in the M298 course, and<br />

four must be passed. An Oral Qualifying Examination<br />

on original research proposed by the candidate<br />

independently of the Ph.D. adviser, and on a topic<br />

distinct and separate from the student' s thesis<br />

research, will be held usually during the student's<br />

second year in the program. A "Midstream Seminar"<br />

is normally presented during the third year<br />

and must be presented at least six months prior to<br />

the Final Oral Examination.<br />

Doctoral Committee . This committee consists of a<br />

minimum of five faculty members from the University,<br />

and must conform to the regulations governing<br />

the nomination of doctoral committees . It must<br />

include three faculty who are "MBI core faculty"<br />

(i.e. have served as research advisers for an MBI<br />

student for at least two years, but who may or may<br />

not<br />

MBI).<br />

be Members, Associates or Affiliates of the<br />

Time to Degree . An oral examination for advancement<br />

to candidacy should be taken, preferably<br />

before the end of the sixth quarter. The average total<br />

time to complete the degree is fifteen quarters. An<br />

oral "midstream " report should be given some time<br />

between being advanced to candidacy and six<br />

months before defense of thesis.<br />

Final Oral Examination . The Final Oral Examination<br />

is required of all students for the degree.<br />

Teaching Experience. Teaching experience is<br />

encouraged<br />

degree.<br />

although it is not a requirement for the<br />

Disqualification and Appeal of Disqualification.<br />

Termination of graduate status may be recommended<br />

by the Chairperson of the Interdepartmental<br />

Ph.D. Committee, after consultation with the<br />

student and his/her adviser (or his/her Student<br />

Guidance Committee). Disqualification may be<br />

recommended if a student fails to maintain an overall<br />

grade point average of 3.0, does not participate<br />

in required elements of the Ph.D. program (including<br />

laboratory rotations and seminars), or fails to<br />

maintain normal progress toward the degree as<br />

outlined under Time to Dc ree and Final Oral<br />

Examination. A recommendation for dismissal may<br />

be appealed to the entire Interdepartmental Ph.D.<br />

Committee; opinions of other interested faculty<br />

members will be considered,<br />

dent.<br />

if requested by the stu-<br />

<strong>Graduate</strong> Courses<br />

M298. Molecular Biology . Seminar in Current<br />

Topics in Molecular Biology. (same as Microbiology<br />

M298, Biological Chemistry M298, Biology M298,<br />

Chemistry M298, and Microbiology and<br />

Immunology (Cell Biology and Virology Section)<br />

M298.)<br />

501. Cooperative Program . (% to 2 courses) Prerequisites:<br />

approval of <strong>UCLA</strong> <strong>Graduate</strong> Adviser<br />

and <strong>Graduate</strong> Dean. Approval of host campus Instructor,<br />

Department Chairman and <strong>Graduate</strong><br />

Dean. The course is used to record the enrollment<br />

of <strong>UCLA</strong> students in courses taken under cooperative<br />

arrangements with neighboring institutions.<br />

To be graded S/U. The Staff<br />

Courses Related to Molecular Biology<br />

The following courses offered by the departments<br />

listed are particularly appropriate to the research<br />

areas mentioned above. With the approval of the<br />

Guidance Committee or Research Supervisor, other<br />

related courses may be included<br />

gram.<br />

in a student's pro-<br />

For specific information regarding the Ph.D. Degree<br />

Program in Molecular Biology, please refer to the<br />

<strong>Graduate</strong> Adviser in that program . For details and<br />

descriptions of the graduate courses offered in<br />

departments related to Molecular Biology, please<br />

refer to the list below.<br />

Departments Related to Molecular Biology<br />

Biological Chemistry M253, 255, 259, M261, M267,<br />

M269, M298.<br />

Biology 225, 227, 229, M233A-2338, 238, 280, 294,<br />

M298.<br />

Chemistry M253, M255, M261, M267, M269, M298.<br />

Microbiology M233A-233B, M258A-258B, 285.<br />

Microbiology and Immunology<br />

Cell Biology and Virology Section 208, 250, 256,<br />

265, M298.<br />

Immunology Section 254, M258A-258B, 261, 262,<br />

264.<br />

Physiology 202, 225.

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