UCLA Graduate Catalog 1980-81 - Registrar - UCLA

234 / PATHOLOGY
will be stressed. To be offered alternate years. 235A,
Fall Quarter, and 235B, Winter Quarter. The Staff
M240 . Immunopathology . (% course ) Lecture, two
hours per week. (Same as Medicine M240.) Prerequisite:
Immunology course and consent of instructor.
Study of the role of immunologic phenomena in
the production of lesions and disease. Topics will
include immuno complex disease, antitissues antibody,
immunologic mediators, cell-mediated
immunity , and infectious diseases.
Mr. Glassock, Mr. Porter
242A. Molecular Mechanisms in Disease. ('h
course ) Prerequisite: course 231A, consent of
instructor. The course concerns itself with a
description of molecular events resulting from administration
of injurious chemical and physical
agents (u.v., x-rays, carcinogens, toxins, etc.) and
from reactions to injuries (e.g., necrosis , degeneration,
hyperplasia , neoplasia , inflammation , etc.);
and also with an interpretation of structural and
functional disturbances in terms of the molecular
alterations. Mr. Van Lancker and the Staff
242B. Molecular Mechanisms in Disease. (%
course) Prerequisite: course 242 or 242A; consent
of instructor. This course is a continuation of
Pathology 242A, both of which concern themselves
with descriptions of molecular events resulting
from administration of injurious chemical and
physical agents (u.v., x-rays, carcinogens, toxin,
etc.) and from reactions to injuries (e.g., necrosis,
degeneration , hyperplasia , neoplasia , inflammation,
etc.); and also with an interpretation of structural
and functional disturbances in terms of
molecular alterations.
Mr. Van Lancker and the Staff
242C. Molecular Mechanisms in Disease. ('h
course ) Prerequisite: course 242A, 242B; consent of
instructor. This course is a continuation of
Pathology 242A and 242B which deal with the
biochemistry and molecular biology of disease processes
produced by nutritional deficiencies,
inherited metabolic errors and the administration
of injurious chemical or physical agents. This particular
segment will cover aspects of neoplasia in
relation to alterations in the control of cell growth,
chemical carcinogenesis and the biology of cancer.
Mr. Moyer and the Staff
244. Electron Microscopy in Experimental
Pathology. (3'4 course) Prerequisite: consent of the
instructor. Ultrastructural aspects of pathology
including introduction to use of modern methods
of electron microscopy in pathological studies,
essentials of normal ultrastructure and ultrastructural
phenomena in general pathology.
Ms. Berliner, Mr. Zamboni
245. Environmental Pathology . Prerequisite: graduate
student status and consent of the instructor.
This course is designed to explore the interrelationships
of man with his total environment. A series of
special topics will be presented to discuss the effect
on man of changes in the compositions of air,
water, soil and other materials. Graded S/U.
Mr. O'Donnell and the Staff
250A- 250B-250C. Pathology Graduate Student
Seminar . Prerequisite: open only to students in
experimental pathology. Required for all pathology
graduate students. Review and discussion of current
literature and research in special topics of
experimental pathology. The Staff
251. Pathology Graduate Student Laboratory Seminar.
Prerequisite : consent of instructor. The course
consists of ten, two-hour seminars which may
include demonstrations of apparatus and methods
dealing with new and advanced experimental techniques
of value in experimental pathology. The
seminars will be conducted by pathology department
staff and guest lecturers. Subjects covered will
include the biochemistry, biological and
morphological techniques in tissue fractionation,
tissue culture and radioautography (electron
microscopy, etc.) that are frequently in the study of
disease mechanisms.
Mr. Lubran, Mr. Rodgerson
*8253 . Free Radical Pathology . (y course ) Lecture,
four and one half hours per week. Prerequisites:
Basic biochemistry, Physical Chemistry. Free radicals,
mechanisms of formation, properties and reactions.
Their reactions with significant biomolecules.
Modes of production in vivo. Reactions in vivo. Protection
against and sensitization towards these
damaging effects. Mr. O'Donnell
M256 . Seminar in Viral Oncology. (% course)
(Same as Microbiology and Immunology M256.) An
advanced research seminar designed to consider
the current developments in the field. Selection of
current subjects and publications dealing with
tumor viruses, oncogenesis, development, and
cellular regulation.
M257. Introduction to Toxicology . (Same as Pharmacology
M257.) Lecture, four hours. Prerequisites:
Pharmacology 241 or consent of instructor.
Biochemical and systemic toxicology, basic
mechanisms of toxicology and the interaction of
toxic agents with specific organ systems.
Dr. Taylor
M258. Pathologic Changes in Toxicology . (Same as
Pharmacology M258.) This course is designed to
give students experience in learning the normal
histology of tissues which are major targets of
Toxin and the range of pathologic changes that
occur in these tissues . Liver, bladder, lung, kidney,
nervous system and vascular system will be
covered. Ms. Berliner
'7260. Quantitative Approaches to Microscopic
Anatomy . ('h course ) Lecture, two hours per week.
Prerequisite: consent of instructor. Practical and
theoretical approaches in the application of
measurement to anatomical structures. General
principles of estimation of volume, surface area and
number will be covered by stereology and other
techniques. Ms. Berliner
M293. Major Concepts in Oncology . (Same as
Microbiology M293, Dentistry/Oral Biology M293,
and Microbiology and Immunology M293.) Prerequisite:
graduate standing or consent of instructor.
Course designed for graduate students contemplating
research in oncology. Lecture. Topics include
cancer pathophysiology, genetics; membranes,
macromolecular synthesis and control, cell cycle,
growth control; physical, chemical and viral
oncogenesis; epidemiology of cancer; tumor
immunology; principles of cancer surgery, radiation
therapy and chemotherapy.
596. Directed Individual Study or Research. (1 to 3
courses ) Individual research with members of our
staff or of other departments, the latter for the purpose
of supplementing programs available in our
department. Graded S/U.
597. Preparation for Qualifying Exams . (% to 2
courses ) Prerequisite: one year of course work in
pathology. Individual study for qualifying exam.
Graded S/U.
599. Preparation of Doctoral Dissertation . ('h to 2
courses ) Prerequisite: completion of qualifying
exam and most of doctoral research. Completion
and writing of thesis. Graded S/U.
PHARMACOLOGY
(Department Office, 23-278 Center for
the Health Sciences)
''John A. Bevan, B.Sc., M.R., B.S., Professor of Pharmacology.
IhArthur K. Cho, Ph.D., Professor of Pharmacology (Vice
Chairman of the Department).
I
hRobert George, Ph.D., Professor of Pharmacology.
thDonald J. Jenden, B.Sc., M.B., U.S.. ProfessorofPharmacology
and Biomathematics (Chairman of the Department).
'('Peter Lomax, M.D., D.Sc., Professor of Pharmacology.
'('Dermot B. Taylor, M.A., M.D., Professor of Pharmacology.
Jeremy H. Thompson, M.D., F.R.C.P.I., Professor of Pharmacology.
Rosemary D. Bevan, M.D., Adjunct Associate Professor of Pharmacology.
Don H. Catlin, M.D., Associate Professor of Pharmacology and
Medicine.
Matthew E. Conolly, M.D., Associate Professor of Pharmacology
and Medicine.
16M. David Fairchild, Ph.D., Adjunct Associate Professor of
Pharmacology.
R. Craig Kammerer, Ph.D., Assistant Professor of Pharmacology.
Larry A. Wheeler, Ph.D., Adjunct Assistant Professor of Pharmacology.
11 Jin Bak, Ph.D., D.D.S., Adjunct Associate Professor of
Neurology and Pharmacology.
Jorge R. Barrio , Ph.D., Associate Professor of Radiological
Sciences and Pharmacology.
Robert O. Bauer, M.D., Professor of Anesthesiology, Obstetrics
and Gynecology and Pharmacology.
Joseph 11. Beckerman, Pharm.D., Lecturer in Pharmacology.
Yi-Han Chang, Ph.D., Adjunct Associate Professor of Medicine
and Pharmacology.
Mark A. Goldberg, M.D., Ph.D., Professor of Neurology and
Pharmacology.
William L. Hewitt , M.D., Professor of Medicine and Pharmacology.
Murray E. Jarvik, M.D., Ph.D., Professor of Pharmacology and
Psychiatry.
Louis Levy, Ph.D., Professor of Medicine and Pharmacology.
The Ph .D. Degree
Admission Requirements. In addition to meeting
the requirements of the Graduate Division, the student
must have received the bachelor's degree in a
biological or physical science or in the premedical
curriculum.
In suitable cases, students who have course deficiencies
may be admitted to graduate status , but any
deficiencies will have to be removed within a
specified time . Graduate Record Examination
scores are required of all applicants to the Department
as well as three (3) letters of recommendation.
Applications are accepted for the Fall Quarter only.
The Departmental Graduate Training Committee
(three faculty members) is solely responsible for the
selection of new students. Interviews may be
requested by the Graduate Training Committee.
Prospective students may write for a departmental
brochure to the following address: Graduate Student
Office, Department of Pharmacology, UCLA
School of Medicine,
(213) 825-5294.
Los Angeles, California 90024,
Advising . Address: Dr. Arthur K. Cho, Graduate
Adviser, Department of Pharmacology, UCLA
School of Medicine, Los Angeles, California 90024,
(213) 825-6567 or 825-5294.
Dr. Cho is the Graduate Adviser for all entering
graduate students and for students in their first and
second year of study. Each student must select his/
her major professor
(sixth quarter).
by the end of the second year
Evaluation of the student's progress is determined
by a series of tests (see section on Written and Oral
Qualifying Examinations). In the Pharmacology
200 course (Laboratory Rotation), a written report
must be submitted by the student to his/her supervisor
and to the Graduate Training Committee.
Transcripts from each quarter are circulated to the
Graduate Training Committee and any student that
appears to not be doing satisfactorily is notified.
Each new student meets with the Graduate Adviser
at least once every quarter and as often as necessary