2012 Proceedings - International Tissue Elasticity Conference
2012 Proceedings - International Tissue Elasticity Conference
2012 Proceedings - International Tissue Elasticity Conference
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Session SIP: Signal and Image Processing<br />
Friday, October 5 8:00A – 10:00A<br />
004 SHEAR WAVE IMAGING USING HARMONIC DISTORTION OF SINUSOIDAL EXCITATION.<br />
Yoshiki Yamakoshi 1 , Parajuli Raj Kumar 1 , Reisen Tei 1 , Daisuke Nakai 1 , Yui Tsuihiji 1 .<br />
1 Gunma University, 1–5–1 Tenjin–cho, Kiryu–shi , Gunma 376–8515 JAPAN.<br />
Background: Continuous shear wave excitation (CSWE) has potential in tissue characterization, and<br />
numerous methods have been proposed in order to reconstruct different kinds of maps [1,2]. For<br />
example, a shear wave propagation map gives information about the mechanical structure of a medium,<br />
such as adhesion and denaturation of tissue. However, the problem of CSWE is that the spatial<br />
resolution is limited by wavelength of shear wave, and it is difficult to introduce high frequency shear<br />
wave due to large attenuation in tissue.<br />
Aims: We propose an imaging method which reconstructs phase modulation component of harmonic<br />
distortion in continuous shear wave excitation.<br />
Methods: A local velocity map is used in order to recover the phase modulation component of shear wave<br />
harmonic distortion. First, the complex displacement map is calculated from an ultrasonic wave Doppler<br />
signal by using cross–correlation of up–sampled radio–frequency (RF) signals. Then, the vibration phase<br />
map is derived. A local velocity map is reconstructed from spatial differentiation of the vibration phase<br />
map along the shear wave propagation direction. When there is no phase modulation in the shear wave,<br />
the local velocity map becomes a shear wave velocity map. But if there is small amplitude phase<br />
modulation, the phase modulation appears on the shear wave velocity map as wave–front pattern of the<br />
harmonic component. The normal direction of the pattern shows the propagation direction, and the<br />
interval between the peaks corresponds to the wavelength. Visibility of the pattern shows the modulation<br />
index. In order to reconstruct the harmonic component of the shear wave, Fourier analysis method is well<br />
known. However, in real–time image reconstruction, spectral resolution of Fourier analysis is not enough<br />
for the harmonic component of small amplitude. The proposed method uses spatial differentiation of the<br />
vibration phase in order to obtain the harmonic component, image of relative high signal–to–noise (S/N)<br />
is obtained when the data acquisition time is limited.<br />
Results: Images which are obtained for an agar gel phantom are shown in Figure 1. The vibration<br />
frequency is 700Hz. Figure 1a is the real part of the complex displacement which shows the wave–front of<br />
the fundamental component of the shear wave. Figure 1b shows the phase modulation component which is<br />
reconstructed by the proposed method. Figure 1c is the real part of complex displacement which is<br />
reconstructed for 3rd order harmonic component by Fourier analysis method. From the result, the wave–front<br />
of small amplitude harmonic distortion, which is difficult to observe by Fourier analysis method, is<br />
reconstructed by the proposed method. In this experiment, harmonic distortion at the vibrator head, which is<br />
measured by 3axes accelerometer, is -47dB (3rd order). Existence of the phase modulation is also observed on<br />
complex displacement vector space. Figure 2 shows an experimental result in vivo (muscle of upper arm). The<br />
vibration frequency is 250Hz. Figure 2a is the shear wave amplitude map for the fundamental component.<br />
Figures 2b and 2c are the local velocity map and the phase modulation component, respectively.<br />
Conclusions: We proposed a visualization method of the harmonic component with small amplitude. Although<br />
the result is preliminary, this map might be useful in observation of mechanical structure of medium.<br />
References:<br />
[1] Y. Yamakoshi, J. Sato, and T. Sato: Ultrasonic Imaging of Internal Vibration of Soft <strong>Tissue</strong> under Forced<br />
Vibration, IEEE Trans. on UFFC, 37, 45–53, 1990.<br />
[2] K. Parker, M. Doyley and D. Rubens: Imaging the Elastic Properties of <strong>Tissue</strong>: The 20 Year Perspective, Phys.<br />
Med. Biol. 56, R1–R29, 2011.<br />
(a) (b) (c)<br />
(a) (b) (c)<br />
Figure 1: Results for agar gel phantom<br />
(a) Complex displacement spectrum map (real part).<br />
(b) Phase modulation map by the proposed method.<br />
(c) 3 rd order harmonic component reconstructed by Fourier<br />
analysis method (real part of complex displacement).<br />
Figure 2: In vivo result (Muscle of upper arm)<br />
(a) Shear wave amplitude map for fundamental component.<br />
(b) Local velocity map by the proposed method.<br />
(c) Phase modulation map reconstructed by the<br />
proposed method.<br />
Vibration frequency is 250Hz.<br />
indicates Presenter 93