Review of the Food-borne Zoonoses Research ... - ARCHIVE: Defra

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4. Other zoonotic pathogens of interest review summary 4.1 Success of research in providing value to Defra Defra has funded research projects on Cryptosporidium, Yersinia and Neospora. Each project was thought to have improved understanding of the zoonotic risk from these pathogens and therefore funding in this area has been of value to Defra. Studies of Cryptosporidium infection confirmed that pets are rarely a source of infection for humans but that some human infections could be attributed to farm animals. Challenge experiments demonstrated for the first time that C. hominis could infect a wide range of farm species, including calves, lambs piglets and poultry. The research on Neospora did not provide evidence that there is a zoonotic risk from cattle. Yersinia enterocolitica strains present in livestock were shown to be a potential threat to human health. 4.2 Issues and areas of concern relating to this research There were no generic issues of concern in this research area. The Yersinia research had generated valuable publications, but it was considered disappointing that more had not been published from the Cryptosporidium work. 4.3 Gaps in research Although additional work could always be carried out, no significant gaps were identified in the research. It was felt that the research agenda in this area should largely be driven by policy needs. There was potential for more work on Cryptosporidium sp. and Yersinia sp. There was not a strong case for Defra to fund further studies on Neospora sp. but a case could be made for working in partnership with industry on Neospora as an endemic disease. Surveillance or prevalence studies would be useful to determine the importance of diseases such as Q fever, toxoplasmosis or Lyme disease in UK livestock. Research to 28
investigate the vulnerability of the UK to infections brought in by exotic pets should also be considered. Other related areas of work in the future might also benefit research on zoonoses. For example, work on detection by array-based technologies would help identify new pathogens and strains emerging in the UK. 4.4 Balance of funding in this research area It was considered necessary for Defra to monitor this area and to have a budget available to enable a rapid response to emerging needs as assessed by Defra and the various specialist advisory groups. 29
Page 2 and 3: Contents Section A - Introduction..
Page 4 and 5: Review of the Food-borne Zoonoses (
Page 6 and 7: Plans for taking forward these prio
Page 8 and 9: Policy Objectives The key policy ob
Page 10 and 11: Figure 2. Laboratory reports of Sal
Page 12 and 13: Figure 4. Laboratory reports of Cam
Page 14 and 15: 6. Aims of the FBZ research review
Page 16 and 17: Section B - Review Summaries 16
Page 18 and 19: epidemiology of Salmonella and anti
Page 20 and 21: There is a need to objectively asse
Page 22 and 23: 2. Campylobacter review summary 2.1
Page 24 and 25: for this organism. Research within
Page 26 and 27: 3. E. coli review summary 3.1 Succe
Page 30 and 31: Annex 1 - Projects Reviewed 30
Page 32 and 33: OZ0311 Conventional versus capillar
Page 34 and 35: OZ0402 OZ0404 OZ0405 OZ0407 OZ0604
Page 36 and 37: OZ0704 OZ0705 OZ0706 OZ0707 Quantif
Page 38 and 39: Annex 2 - Project Abstracts and Pro
Page 40 and 41: To test the suitability of the AFLP
Page 42 and 43: Project code: OZ0324 Project title:
Page 46 and 47: Review Summary The knowledge that t
Page 48 and 49: Review Summary The project was felt
Page 52 and 53: It is clear that the EC legislative
Page 54 and 55: if the vaccines currently available
Page 56 and 57: Four published papers have come out
Page 58 and 59: Review Summary This epidemiological
Page 60 and 61: Project code: OZO316 Project title:
Page 64 and 65: agricultural industry/public health
Page 66 and 67: testing laboratories. In addition,
Page 68 and 69: animal pathogen but is a human path
Page 70 and 71: esearch has also substantially impr
Page 72 and 73: to elucidate the antigenic repertoi
Page 74 and 75: and have contributed to our underst
Page 76 and 77: Fundamental issues concerning the f
Page 78 and 79:
Review summary Project OZ0606 focus
Page 80 and 81:
Abstract of research OZ0608 The ado
Page 82 and 83:
thinning process for molecular trac
Page 84 and 85:
Project code: LK0665 Project title:
Page 86 and 87:
Review summary While poultry meat i
Page 88 and 89:
Review summary A key aim of this pr
Page 90 and 91:
Review summary This project aimed t
Page 92 and 93:
Project code: OZ0709 Project title:
Page 94 and 95:
Page 96 and 97:
Project code: OZ0138C Project title
Page 98 and 99:
Page 100 and 101:
Page 102 and 103:
Abstract of research Projects OZ070
Page 104 and 105:
produced were both relevant and imp
Page 106 and 107:
List of External Reviewers. Mr. Pau
Page 108 and 109:
Review of Defra’s FBZ Research Pr
Page 110 and 111:
Review of Defra’s FBZ Research Pr
Page 112 and 113:
Annex 5 - Review Timetable 112
Page 114 and 115:
11.45 - 12.00 Bovine and Porcine Fo
Page 116:
Campylobacter Other 11.50 - 12.05 P
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Review of the Food-borne Zoonoses Research ... - ARCHIVE: Defra

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