Review of the Food-borne Zoonoses Research ... - ARCHIVE: Defra

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Review summary Project OZ0606 focused on the dynamics of intestinal colonisation of chickens with campylobacter, including the effect of competitive exclusion and immune responses during colonisation. This project has demonstrated a clear link between maternal immunity and the colonisation lag phase in chicks, and also identified factors that could be used in control of campylobacter. OZ0606 has also increased knowledge of the use of competitive exclusion products in the laboratory environment. The results from this project showed promise but unfortunately the researchers have had difficulty replicating their work in the subsequent project (OZ0614). This is a difficult research area, however the widespread nature of campylobacter, and the lack of success in controlling this organism through biosecurity, highlights the necessity of progressing the vaccination approach. 78
Project code: OZ0608 Project title: Epidemiological studies and development of practical control measures for Campylobacter in broiler flocks Start date (dd/mm/yy): 01/07/02 End date (dd/mm/yy): 30/06/06 £859,393 Total cost: Affiliation: Veterinary Laboratories Agency Sub-contractor(s): Co-contractor - University of Bristol Sub-contractor - Imperial College Project code: OZ0610 Project title: Survival and persistence of campylobacters in poultry farm environments and suggested control measures Start date (dd/mm/yy): 01/09/05 End date (dd/mm/yy): 31/01/09 £746,102.00 Total cost: Affiliation: University of Bristol Sub-contractor(s): Co-contractor - VLA Sub-contractors - SAC, DTA Ltd Project code: OZ0613 Project title: Towards risk-based control of Campylobacter: developing the evidence base using epidemiological and bacteriological approaches Start date (dd/mm/yy): 01/01/06 End date (dd/mm/yy): 30/09/10 Total cost: £1,558,693 (Defra: £1,495,693; Other funders: £200,000) Affiliation: Veterinary Laboratories Agency Sub-contractor(s): 79
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Contents Section A - Introduction..
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Review of the Food-borne Zoonoses (
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Plans for taking forward these prio
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Policy Objectives The key policy ob
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Figure 2. Laboratory reports of Sal
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Figure 4. Laboratory reports of Cam
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6. Aims of the FBZ research review
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Section B - Review Summaries 16
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epidemiology of Salmonella and anti
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There is a need to objectively asse
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2. Campylobacter review summary 2.1
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for this organism. Research within
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3. E. coli review summary 3.1 Succe
Page 28 and 29: 4. Other zoonotic pathogens of inte
Page 30 and 31: Annex 1 - Projects Reviewed 30
Page 32 and 33: OZ0311 Conventional versus capillar
Page 34 and 35: OZ0402 OZ0404 OZ0405 OZ0407 OZ0604
Page 36 and 37: OZ0704 OZ0705 OZ0706 OZ0707 Quantif
Page 38 and 39: Annex 2 - Project Abstracts and Pro
Page 40 and 41: To test the suitability of the AFLP
Page 42 and 43: Project code: OZ0324 Project title:
Page 46 and 47: Review Summary The knowledge that t
Page 48 and 49: Review Summary The project was felt
Page 52 and 53: It is clear that the EC legislative
Page 54 and 55: if the vaccines currently available
Page 56 and 57: Four published papers have come out
Page 58 and 59: Review Summary This epidemiological
Page 60 and 61: Project code: OZO316 Project title:
Page 64 and 65: agricultural industry/public health
Page 66 and 67: testing laboratories. In addition,
Page 68 and 69: animal pathogen but is a human path
Page 70 and 71: esearch has also substantially impr
Page 72 and 73: to elucidate the antigenic repertoi
Page 74 and 75: and have contributed to our underst
Page 76 and 77: Fundamental issues concerning the f
Page 80 and 81: Abstract of research OZ0608 The ado
Page 82 and 83: thinning process for molecular trac
Page 84 and 85: Project code: LK0665 Project title:
Page 86 and 87: Review summary While poultry meat i
Page 88 and 89: Review summary A key aim of this pr
Page 90 and 91: Review summary This project aimed t
Page 96 and 97: Project code: OZ0138C Project title
Page 102 and 103: Abstract of research Projects OZ070
Page 104 and 105: produced were both relevant and imp
Page 106 and 107: List of External Reviewers. Mr. Pau
Page 108 and 109: Review of Defra’s FBZ Research Pr
Page 110 and 111: Review of Defra’s FBZ Research Pr
Page 112 and 113: Annex 5 - Review Timetable 112
Page 114 and 115: 11.45 - 12.00 Bovine and Porcine Fo
Page 116: Campylobacter Other 11.50 - 12.05 P
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