Research Report 2010 2011 - Helmholtz-Zentrum für ...

166 SCIENTIFIC REPORTS | Publications
• Lefever,T., Pedersen,E., Basse,A., Paus,R., Quondamatteo,F.,
Stanley,A.C., Langbein,L., Wu,X., Wehland,J., Lommel,S., &
Brakebusch,C. (2010) N-WASP is a novel regulator of hair-follicle
cycling that controls antiproliferative TGF{beta} pathways. Journal of
Cell Science 123, 128-140.
• Leonhardt,J., Kuebler,J.F., Turowski,C., Tschernig,T., Geffers,R., &
Petersen,C. (2010) Susceptibility to experimental biliary atresia
linked to different hepatic gene expression profiles in two mouse
strains. Hepatology Research 40, 196-203.
• Macke,L., Garritsen,H.S., Meyring,W., Hannig,H., Pagelow,U.,
Wormann,B., Piechaczek,C., Geffers,R., Rohde,M., Lindenmaier,W.,
& Dittmar,K.E.*. (2010) Evaluating maturation and genetic modification
of human dendritic cells in a new polyolefin cell culture bag
system. Transfusion 50, 843-855.
• Micklinghoff,J.C., Schmidt,M., Geffers,R., Tegge,W., & Bange,F.C.
(2010) Analysis of expression and regulatory functions of the
ribosome-binding protein TypA in Mycobacterium tuberculosis under
stress conditions. Archives of Microbiology 192, 499-504.
• Pils,M.C., Pisano,F., Fasnacht,N., Heinrich,J.M., Gröbe,L.,
Schippers,A., Rozell,B., Jack,R.S., & Muller,W. (2010) Monocytes/
macrophages and/or neutrophils are the target of IL-10 in the LPS
endotoxemia model. European Journal of Immunology 40, 443-448.
• Quiel,A., Jurgen,B., Piechotta,G., Le Foll,A.P., Ziebandt,A.K., Kohler,C.,
Koster,D., Engelmann,S., Erck,C., Hintsche,R., Wehland,J., Hecker,M.,
& Schweder,T. (2010) Electrical protein array chips for the detection
of staphylococcal virulence factors. Applied Microbiology and Biotechnology
85, 1619-1627.
• Stegmann,K.A., Björkström,N.K., Liermann,H., Ciesek,S., Riese,P.,
Wiegand,J., Hadem,J., Suneetha,P.V., Jaroszewicz,J., Wang,C.,
Schlaphoff,V., Fytili,P., Cornberg,M., Manns,M.P., Geffers,R.,
Pietschmann,T., Guzmán,C.A.*., Ljunggren,H.-G., & Wedemeyer,H.
(2010) IFN alpha-induced TRAIL on human NK cells is associated
with control of hepatitis C virus infection. Gastroenterology 138,
1885-1897.
• Steinweg,C., Kuenne,C.T., Billion,A., Mraheil,M.A., Domann,E.,
Ghai,R., Barbuddhe,S.B., Karst,U., Goesmann,A., Puhler,A.,
Weisshaar,B., Wehland,J., Lampidis,R., Kreft,J., Goebel,W.,
Chakraborty,T., & Hain,T. (2010) Complete genome sequence of Listeria
seeligeri, a nonpathogenic member of the genus Listeria. Journal
of Bacteriology 192, 1473-1474.
• Trunk,K., Benkert,B., Quack,N., Munch,R., Scheer,M., Garbe,J.,
Jänsch,L., Trost,M., Wehland,J., Buer,J., Jahn,M., Schobert,M., &
Jahn,D. (2010) Anaerobic adaptation in Pseudomonas aeruginosa:
definition of the Anr and Dnr regulons. Environmental Microbiology
12, 1719-1733.
• Wilke,S., Krausze,J., Gossen,M., Gröbe,L., Jager,V., Gherardi,E., van
den,H.J., & Bussow,K. (2010) Glycoprotein production for structure
analysis with stable, glycosylation mutant CHO cell lines established
by fluorescence-activated cell sorting. Protein Science 19, 1264-1271.
• Froese,N., Kattih,B., Breitbart,A., Grund,A., Geffers,R., Molkentin,J.D.,
Kispert,A., Wollert,K.C., Drexler,H., & Heineke,J. (2011) GATA6
promotes angiogenic function and survival in endothelial cells by
suppression of autocrine transforming growth factor beta/activin
receptor-like kinase 5 signaling. Journal of Biological Chemistry
286(7), 5680-5690
• Lorenz,U., Lorenz,B., Schmitter,T., Streker,K., Erck,C., Wehland,J.,
Nickel,J., Zimmermann,B., & Ohlsen,K. (2011) Functional antibodies
targeting IsaA of Staphylococcus aureus augment host immune
response and open new perspectives for antibacterial therapy. Antimicrobial
Agents and Chemotherapy 55, 165-173.
• Schenk,U., Frascoli,M., Proietti,M., Geffers,R., Traggiai,E., Buer,J.,
Ricordi,C., Westendorf,A.M., & Grassi,F. (2011) ATP inhibits the
generation and function of regulatory T cells through the activation
of purinergic P2X receptors. Science Signaling 4, ra12.
• Kusch,K., Hanke,K., Holtfreter,S., Schmudde,M., Kohler,C., Erck,C.,
Wehland,J., Hecker,M., Ohlsen,K., Bröker,B. & Engelmann,S. (2011)
The influence of SaeRS and σ B on the expression of superantigens
in different Staphylococcus aureus isolates. International Journal of
Microbiology, in press
• TrehanPati,N., Sukriti,S., Geffers,R., Hissar,S., Riese,P., Toepfer,T.,
Buer,J., Adams,D.H., Guzmán,C.A.*, & Sarin,S.K. (2011) Acute and
resolving phase of HEV infected patients and its cellular immune
and global gene expression patterns. Journal of Clinical Immunology,
in press
Former RG Cytoskeleton Dynamics | Prof. Dr. Klemens Rottner
• Hanisch,J., Ehinger,J., Ladwein,M., Rohde,M., Derivery,E., Bosse,T.,
Steffen,A., Bumann,D., Misselwitz,B., Hardt,W.D., Gautreau,A.,
Stradal,T.B.*., & Rottner,K. (2010) Molecular dissection of Salmonella-induced
membrane ruffling versus invasion. Cellular Microbiology
12, 84-98
• Hertzog,M., Milanesi,F., Hazelwood,L., Disanza,A., Liu,H., Perlade,E.,
Malabarba,M.G., Pasqualato,S., Maiolica,A., Confalonieri,S., Le,C.C.,
Offenhauser,N., Block,J., Rottner,K., Di Fiore,P.P., Carlier,M.F.,
Volkmann,N., Hanein,D., & Scita,G. (2010) Molecular basis for the
dual function of Eps8 on actin dynamics: bundling and capping.
PLoS Biology 8, e1000387.
• Klink,B.U., Barden,S., Heidler,T.V., Borchers,C., Ladwein,M.,
Stradal,T.B.*., Rottner,K., & Heinz,D.W.*. (2010) Structure of Shigella
IpgB2 in complex with human RhoA: implications for the mechanism
of bacterial guanine nucleotide exchange factor mimicry. Journal of
Biological Chemistry 285, 17197-17208.
• Marg,S., Winkler,U., Sestu,M., Himmel,M., Schonherr,M., Bar,J.,
Mann,A., Moser,M., Mierke,C.T., Rottner,K., Blessing,M., Hirrlinger,J.,
& Ziegler,W.H. (2010) The vinculin-DeltaIn20/21 mouse: characteristics
of a constitutive, actin-binding deficient splice variant of vinculin.
PLoS ONE 5, e11530.
• Rottner,K., Hanisch,J., & Campellone,K.G. (2010) WASH, WHAMM
and JMY: regulation of Arp2/3 complex and beyond. Trends in Cell
Biology 20, 650-661.
• Jackson,B., Peyrollier,K., Pedersen,E., Basse,A., Karlsson,R., Wang,Z.,
Lefever,T., Ochsenbein,A.M., Schmidt,G., Aktories,K., Stanley,A.,
Quondamatteo,F., Ladwein,M., Rottner,K., van,H.J., & Brakebusch,C.
(2011) RhoA is dispensable for skin development, but crucial for contraction
and directed migration of keratinocytes. Molecular Biology of
the Cell 22, 593-605.
Former RG Signalling and Motility | Prof. Dr. Theresia Stradal
• Hanisch,J., Ehinger,J., Ladwein,M., Rohde,M., Derivery,E., Bosse,T.,
Steffen,A., Bumann,D., Misselwitz,B., Hardt,W.D., Gautreau,A.,
Stradal,T.B.*., & Rottner,K. (2010) Molecular dissection of Salmonella-induced
membrane ruffling versus invasion. Cellular Microbiology
12, 84-98.
• Klink,B.U., Barden,S., Heidler,T.V., Borchers,C., Ladwein,M.,
Stradal,T.B.*., Rottner,K., & Heinz,D.W.*. (2010) Structure of Shigella
IpgB2 in complex with human RhoA: implications for the mechanism
of bacterial guanine nucleotide exchange factor mimicry. Journal of
Biological Chemistry 285, 17197-17208.
• Stradal,T.B.*. & Backert,S. (2010) Host-pathogen interaction: How
EHEC influence the actin cytoskeleton of the host cell [Wirt-Pathogen-Interaktion
wie EHEC das Aktinzytoskelett der Wirtszelle beeinflussen].
Biospektrum 16, 624-627.
• Tahirovic,S., Hellal,F., Neukirchen,D., Hindges,R., Garvalov,B.K.,
Flynn,K.C., Stradal,T.E.*., Chrostek-Grashoff,A., Brakebusch,C., &
Bradke,F. (2010) Rac1 regulates neuronal polarization through the
WAVE complex. Journal of Neuroscience 30, 6930-6943.