terminology and guidelines for glaucoma ii - Kwaliteitskoepel
terminology and guidelines for glaucoma ii - Kwaliteitskoepel
terminology and guidelines for glaucoma ii - Kwaliteitskoepel
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Pregnancy <strong>and</strong> nursing mothers<br />
Only to be used if the potential benefit justifies the potential risk to the fetus or the infant.<br />
Drug interactions<br />
Oral or intravenous calcium antagonists: caution should be used in the co-administration of beta-adrenergic<br />
blocking agents <strong>and</strong> oral or intravenous calcium antagonists, because of possible atrioventricular conduction disturbances,<br />
left ventricular failure, <strong>and</strong> hypotension.<br />
Digitalis <strong>and</strong> calcium antagonists: the concomitant use of beta-adrenergic blocking agents with digitalis may have<br />
additive effects in prolonging conduction time.<br />
Catecholamine-depleting drugs: possible additive effects <strong>and</strong> the production of hypotension <strong>and</strong>/or marked bradycardia.<br />
Wash-out<br />
The time needed <strong>for</strong> beta blockers & latanoprost to lose their activity completely is 2-5 weeks.<br />
THE WASH-OUT TIME NEEDED FOR A TOPICALLY ADMINISTERED DRUG<br />
TO COMPLETELY LOSE ITS EFFECT VARIES GREATLY<br />
Betablockers<br />
Sympathomimetics<br />
Direct acting miotics<br />
Indirect-acting miotics<br />
Topical CAI<br />
Oral CAI<br />
Prostagl<strong>and</strong>ins/ Prostamides<br />
2-5 weeks<br />
2 weeks<br />
1-3 days<br />
1 month-permanent<br />
1 week<br />
1 week<br />
4-6 weeks<br />
Ch. 3 - 26 EGS