PDF catalog - Teknolab AS

FORENSIC AND CLINICAL
PRODUCTS FOR FORENSIC AND CLINICAL APPLICATIONS
Biotage produces a wide range of products for use in the area of forensic toxicology and doping control in animal
and human sports.
EVOLUTE SPE Columns
NEW EVOLUTE ABN and CX SPE products are ideal for robust extraction of drugs from plasma, urine and whole
blood samples. Optimised sorbents provide clean extracts with minimal LC-MS/MS matrix effects due to
proteins, salts and phospholipids. Formats optimised for high throughput applications and viscous samples are
now available. See www.biotage.com for the latest applications.
See pages 24-27 for ordering information
ISOLUTE Confirm HCX Columns for High Extract Purity
Extract basic drugs from biological fluids with ISOLUTE
Confirm HCX mixed mode SPE
columns that provide two primary retention mechanisms,
non-polar (C8) and strong cation exchange.
GC-MS
(TIC)
This dual retention mechanism allows a rigorous interference
elution regime to be used without reducing recovery of the
analytes of interest when compared to non-selective LLE, resin
or C18 based methodologies. ISOLUTE Confirm HCX columns
provide extremely high purity extracts of drugs of abuse from
biological fluids such as urine, plasma and whole blood (see
figure 1).
Biotage’s range of reservoirs and sorbent bed mass options
ensure automation compatibility and capacity requirement of
diverse sample matrices such as hydrolyzed hair, equine urine
and whole blood. Improved flow characteristics for more viscous
samples, reducing the possibility of column plugging, is
provided by wider column diameters.
Figure 1. Chromatogram (GC-MS in TIC mode) was
obtained by extracting 5 mL urine spiked at the
NIDA cut-off level of 100 ng/mL with:
1. Amphetamine 2. Methamphetamine
3. Phencyclidine 4. Cocaine
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