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PDF catalog - Teknolab AS

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FORENSIC AND CLINICAL<br />

PRODUCTS FOR FORENSIC AND CLINICAL APPLICATIONS<br />

ISOLUTE HM-N Supported Liquid Extraction (SLE) Columns<br />

Supported liquid extraction is a popular approach for<br />

drugs of abuse extraction in forensic analysis. Optimized<br />

to provide high recoveries from biological fluids, ISOLUTE<br />

HM-N columns are packed with a modified form of<br />

diatomaceous earth. Designed for processing under gravity,<br />

these simple to use columns are a high productivity<br />

alternative to liquid-liquid extraction.<br />

ISOLUTE HM-N column ordering information can be found<br />

on page 93.<br />

IST Gravity Rack ordering information can be found on<br />

page 110.<br />

Products for Doping Control Applications<br />

ISOLUTE C8, C18 and ENV+ columns are ideal for applications in doping control in sport such as the extraction<br />

of steroids and their glucuronide and sulphate metabolites from human urine. For example, ISOLUTE C8 is used<br />

to extract 5 α−dihydrotestosterone from athlete’s urine (ref. Kicman et al, Clinical Chemistry, 1995, 41/11,<br />

1617-1627).<br />

For ISOLUTE non-polar sorbents ordering information, see pages 30-49.<br />

Extraction of Catecholamines from Urine and Plasma<br />

Simple SPE procedures for catecholamine extraction have been developed based on the retention of a diphenyl<br />

boronate-catecholamine complex on an ISOLUTE MFC18 SPE column. The free catecholamines are generated by<br />

treating the extract with acid.<br />

Request Application Notes IST1043 (plasma) and IST1047 and IST1071 (urine) for more information.<br />

Ordering information for ISOLUTE MFC18 SPE columns can be found on page 38.<br />

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