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PDF catalog - Teknolab AS

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EXCH<br />

ION EXCHANGE SORBENTS<br />

Isolate ionizable (acidic or basic) analytes from aqueous or partially aqueous sample matrices using ion<br />

exchange retention mechanisms. The technical information for Biotage’s range of ISOLUTE ion exchange<br />

sorbents is summarized on these pages.<br />

ISOLUTE Anion Exchange Sorbents<br />

ISOLUTE anion exchange sorbents are used for the extraction of acidic compounds. Weak anion exchange<br />

sorbents (ISOLUTE NH2 and PSA) are suitable for the isolation of strongly acidic analytes (e.g. those containing<br />

sulfonic acid groups) or analytes that are unstable under acidic conditions. The sorbents’ positive charge can<br />

be eliminated by pH control, for analyte elution.<br />

ISOLUTE Anion Exchange Sorbents<br />

Sorbent Description Structure Average Particle<br />

Size (µm)<br />

Pore<br />

Diameter<br />

(Å)<br />

NH2 Aminopropyl -Si-(CH 2 ) 3 NH 2 50 60<br />

PSA<br />

Ethylenediamine-N-propyl<br />

(non-endcapped)<br />

-Si-(CH 2 ) 3 NH(CH 2 ) 2 NH 2 50 60<br />

SAX<br />

PE-AX<br />

Quaternary amine (chloride<br />

counter ion)<br />

Quaternary amine (acetate<br />

counter ion)<br />

-Si-(CH 2 ) 3 N + (CH 3 ) 3 Cl - 50 60<br />

-Si-(CH 2 ) 3 N + (CH 3 ) 3 OAc - 50 60<br />

60

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