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PDF catalog - Teknolab AS

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EVOLUTE<br />

ADVANCED POLYMERIC SORBENTS FOR OPTIMIZED SAMPLE PREP<br />

EVOLUTE ®<br />

Sample Preparation Products<br />

EVOLUTE ® Sample Preparation Products are<br />

advanced water-wettable polymer-based sorbents.<br />

Developed specifically for analyte quantification by<br />

LC-MS/MS, EVOLUTE products provide a highly<br />

effective solution to the problems of ion<br />

suppression and matrix effects from dirty extracts.<br />

These high performance products allow scientists<br />

to use generic methodologies to reduce method<br />

development time while producing clean extracts<br />

for a wide range of compounds.<br />

Features and Advantages<br />

• 40Å pore size and narrow pore size distribution provides cleaner extracts and reduced matrix effects<br />

• Pore size also provides for improved signal to noise in LC-MS for lower detection levels<br />

• Generic methodology means method development is fast and simple<br />

• High quality leads to reproducible recoveries for a wide range of analytes<br />

The EVOLUTE Family of sorbents has a uniquely modified surface structure that is water-wettable to promote<br />

robust, reliable sample preparation. They also have an optimized pore structure that minimizes the retention<br />

of high molecular weight endogenous materials present in complex sample matrices. The result is cleaner<br />

extracts, compared to other leading polymer based SPE products.<br />

Generic methods for high analyte recoveries<br />

EVOLUTE ABN has a balanced combination of polar (hydrophilic) and non-polar (hydrophobic) interactions,<br />

which, combined with simple generic methodology, allows simultaneous extraction of acidic, basic and neutral<br />

analytes of wide ranging polarity.<br />

EVOLUTE CX is a mixed-mode sorbent combining a water-wettable surface with uniform coverage of sulfonic<br />

acid (SO 3<br />

- ) groups with optimum exchange capacity. Generic methodology is available to provide greater than<br />

85% recovery for a wide range of basic analytes from biological fluids and other aqueous matrices.<br />

Excellent flow characteristics<br />

EVOLUTE sorbents have a narrow particle size distribution providing consistent flow characteristics for a variety<br />

of sample matrices, and resulting in reliable performance during automated sample processing. Optimized packing<br />

techniques eliminate channeling, which can lead to analyte breakthrough.<br />

EVOLUTE 30 µm sorbents are available in small volume columns and 96-well plates optimized for bioanalytical<br />

sample preparation.<br />

EVOLUTE 50 µm sorbents are optimized for processing larger volume or higher viscosity samples in environmental,<br />

food safety, clinical, forensic and doping control applications.<br />

22<br />

Batch-to-batch reproducibility<br />

The chemical and physical characteristics of every batch of EVOLUTE sorbent are quality controlled and tested<br />

to ensure consistency.

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