Program Book - Confex

ACR CURRENT ABSTRACT SESSIONS
9:00 - 10:30 am
W196a
Cytokines, Mediators, and Gene Regulation III
Moderators: Shiva Shahrara, PhD; University of Illinois at
Chicago; Chicago, IL
Pierre Miossec, MD, PhD; Immunogenomics and Inflammation
Research Unit; Lyon, France
9:00 am
2567. Immune Suppression and Injury Tolerance in Fibrotic
Liver Are Mediated by Induced Regulatory T Cells Which
Safeguard Fibroplasias From Clearance
Ming Feng 1 , Yuan-Ping Han 1 and Song G. Zheng 2 , 1 University
of Southern California, Los Angeles, CA, 2 USC Keck School of
Medicine, Los Angeles, CA
9:15 am
2568. Activation of c-Jun N-Terminal Kinase and Extracellular
Signal-Regulated Kinase Predicts Damage in Systemic Lupus
Erythematosus
Mirit Amit-Vazina 1 , Yair Molad 2 , Eliyahu Yona 3 , Lily Amram 3 , Olga
Bloch 4 and Micha J. Rapoport 4 , 1 Rheumatology Service, Assaf
Harofeh Medical Center and Sackler School of Medicine, Tel-Aviv
University, Israel, Zerifin, Israel, 2 Rheumatology Unit, Beilinson
Hospital, Rabin Medical Center, and Sackler Faculty of Medicine,
Tel Aviv University, Petah Tikva, Israel, 3 Internal Medicine
Division, Day Care Unit, Assaf Harofeh Medical Center and
Sackler School of Medicine, Tel-Aviv University, Israel, Zerifin,
Israel, 4 Diabetes and Immunology Research Laboratory, Assaf
Harofeh Medical Center and Sackler School of Medicine, Tel-Aviv
University, Israel, Zerifin, Israel
9:30 am
2569. Novel Regulation of TNF-α-Induced-IL-18 Bioactivity
in Rheumatoid Arthritis Synovial Fibroblasts by Reducing
Caspase-1 Via JAK2 Inhibition
Hubert Marotte 1 , Tatiana Fedorova 1 , Adam J. Pinney 1 , Benjamin
Lewis 1 and Alisa E. Koch 2 , 1 University of Michigan Medical
School, Ann Arbor, MI, 2 Veteran’s Administration and Unversity
of Michigan, Ann Arbor, MI
9:45 am
2570. STAT3 Phosphorylation of Circulating Leukocytes
Correlates with Disease Activity in Early Untreated Rheumatoid
Arthritis
Krista Kuuliala 1 , Antti Kuuliala 1 , Saara Aittomäki 1 , Suvi Oksanen 1 ,
Sanna Siitonen 2 , Hannu Kautiainen 3 , Marjatta Leirisalo-Repo 2 and
Heikki Repo 1 , 1 Haartman Institute, Helsinki, Finland, 2 Helsinki
University Central Hospital, Helsinki, Finland, 3 Central Finland
Central Hospital, Jyväskylä, Finland
10:00 am
2571. What Keeps An Autoantibody-Positive Healthy Individual
Healthy
Lauren L. Ritterhouse 1 , Holden T. Maecker 2 , Hongwu Du 3 , C.
Garrison Fathman 4 , Joan T. Merrill 1 , Joel Guthridge 1 and Judith
A. James 5 , 1 Oklahoma Medical Research Foundation, Oklahoma
City, OK, 2 University School of Medicine, Stanford, CA, 3 Stanford
University School of Medicine, Stanford, CA, 4 Stanford Univ
Medical Center, Stanford, CA, 5 Oklahoma Medical Research
Foundation and Oklahoma University Health Sciences Center,
Oklahoma City, OK
10:15 am
2572. Aminopeptidase N/CD13 Localization and Chemotaxis in
Rheumatoid Arthritis In Vivo and In Vitro
Rachel Morgan 1 , Nilofar Behbahani-Nejad 1 , Judith Endres 1 and
David A. Fox 2 , 1 University of Michigan, Ann Arbor, MI, 2 Univ of
Michigan Med Ctr, Ann Arbor, MI
W194b
Epidemiology and Health Services Research III:
Rheumatoid Arthritis
Moderators: Gabriela Schmajuk, MD, MS; University of
California San Francisco; San Francisco, CA
Elizabeth W. Karlson, MD, MPH; Brigham and Women’s Hospital;
Boston, MA
9:00 am
2573. Administrative Definitions of Rheumatoid Arthritis:
Rising Prevalence Regardless of Definition Used
Christine A. Peschken 1 , Carol A. Hitchon 2 , Hui Chen 2 , Allan
Garland 2 , Hani S. El-Gabalawy 2 , Charles N. Bernstein 2 and Ruth
Ann Marrie 2 , 1 Univ of Manitoba, Winnipeg, MB, 2 University of
Manitoba, Winnipeg, MB
9:15 am
2574. The Association of Ambient Air Pollution Exposures and
Risk of Rheumatoid Arthritis: Results From the Swedish EIRA
Case-Control Study and the US Nurses’ Health Prospective
Cohort Study
Jaime E. Hart 1 , Henrik Källberg 2 , Francine Laden 3 , Karen
H. Costenbader 1 , Marie Holmqvist 2 , Lars Klareskog 2 , Lars
Alfredsson 4 and Elizabeth W. Karlson 1 , 1 Brigham and Women’s
Hospital, Boston, MA, 2 Karolinska Institutet, Stockholm, Sweden,
3
Harvard School of Public Health, Boston, MA, 4 Institute of
Environmental Medicine, Unit of Cardiovascular Epidemiology,
Karolinska Institutet, Stockholm, Sweden
9:30 am
2575. The Performance of Matrix-Based Risk Models for
Rapid Radiographic Progression in An Observational Cohort of
Established RA Patients
Siri Lillegraven 1 , Femke H.M. Prince 2 , Nancy A. Shadick 2 , Espen
A. Haavardsholm 3 , Michelle A. Frits 2 , Christine K. Iannaccone 2 ,
Tore K. Kvien 3 , Michael E. Weinblatt 2 and Daniel H. Solomon 2 ,
1
Brigham and Women’s Hospital / Diakonhjemmet Hospital,
Boston / Oslo, MA, 2 Brigham and Women’s Hospital, Boston,
MA, 3 Diakonhjemmet Hospital, Oslo, Norway
9:45 am
2576. Are Biologics Cost-Effective Analysis Based on Real-Life
Rheumatoid Arthritis Patients
Hawre Jalal 1 , Kaleb Michaud 2 , Hyon K. Choi 3 , Young Hee Rho 3
and Karen Kuntz 1 , 1 University of Minnesota, Minneapolis, MN,
2
National Data Bank for Rheumatic Diseases & University of
Nebraska Medical Center, Omaha, NE, 3 Boston University School
of Medicine, Boston, MA
10:00 am
2577. Statins and Risk of Acute Myocardial Infarction in
Patients with RheumatoidArthritis: A Population-Based Study
Mary De Vera 1 , Diane Lacaille 1 , Michal Abrahamowicz 2 , Jacek
WEDNESDAY
WEDNESDAY
November 9, 2011
2011 Program Book 119