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Program Book - Confex

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ACR/ARHP Poster Session B<br />

Rheumatic Diseases, Pune, India, 3 Sinhgad College of<br />

Engineering, Pune, India, 4 Gokhale Institute of Politics and<br />

Economics, Pune, India, 5 Symbiosis International University,<br />

Pune - 41104 2 , India<br />

1256. Design of a High Potency CTLA4-Ig with Extended Half-Life<br />

for Improved Dosing Convenience. Matthew J. Bernett,<br />

Seung Y. Chu, Holly M. Horton, Erik Pong, Irene Leung,<br />

Gregory L. Moore, Umesh S. Muchhal, Greg A. Lazar,<br />

David E. Szymkowski and John R. Desjarlais, Xencor, Inc.,<br />

Monrovia, CA<br />

1257. Campylobacter Fetus Infection In Three Patients<br />

Treated with Rituximab for Rheumatoid Arthritis.<br />

Alain Meyer 1 , Arnaud Theulin 2 , Emmanuel Chatelus 3 ,<br />

Christelle Sordet 2 , Rose-Marie Javier 2 , Helene Chifflot 4 ,<br />

Jacques-Eric Gottenberg 5 and Jean Sibilia 6 , 1 Hautepierre<br />

Strasbourg university, Strasbourg, France, 2 Hautepierre<br />

Strasbourg Hospital University, Strasbourg, France, 3 Hopital<br />

Hautepierre, Strasbourg, France, 4 Hautepierre Strasbourg<br />

Hospital University, 6 7000, France, 5 Strasbourg University<br />

Hospital, Strasbourg, France, 6 Service de rhumatologie,<br />

Hôpitaux Universitaires de Strasbourg, Strasbourg, France,<br />

Strasbourg, France<br />

1258. Short- and Long-Term Effect of Unguided, Intra-Articular<br />

Injections with Betamethasone In Early Rheumatoid<br />

Arthritis. Impact of Joint Area, Repeated Injections, MRI<br />

Findings, Anti-CCP, IgM-RF and CRP. Merete L. Hetland 1 ,<br />

Mikkel Østergaard 2 , Bo J. Ejbjerg 3 , Søren Jacobsen 4 , Kristian<br />

Stengaard-Pedersen 5 , Peter Junker 6 , Tine Lottenburger 6 , Ib<br />

Hansen 7 , Lis Smedegaard Andersen 8 , Ulrik Tarp 9 , Anders<br />

Svendsen 10 , Jens Kristian Pedersen 6 , Henrik Skjødt 11 ,<br />

Torkell Ellingsen 12 , Hanne M. Lindegaard 6 and Kim<br />

Hørslev-Petersen 13 , 1 Copenhagen University Hospital at<br />

Glostrup, on behalf of DANBIO, Copenhagen, Denmark,<br />

2<br />

Copenhagen University Hospital in Glostrup, Glostrup,<br />

Denmark, 3 Hospital at Slagelse, Slagelse, Denmark,<br />

4<br />

Rigshospitalet - 4242, Copenhagen, Denmark, 5 Department<br />

of Rheumatology, Aarhus University Hospital, Aarhus,<br />

Denmark, 6 Odense University Hospital, Odense C, Denmark,<br />

7<br />

Viborg Hospital, Viborg, Denmark, 8 Denmark, 9 Aarhus<br />

University Hospital, Aarhus, Denmark, 10 Odense, Denmark,<br />

11<br />

Copenhagen University Hospital at Glostrup, Copenhagen,<br />

Denmark, 12 University Hospital, Silkeborg, Denmark,<br />

13<br />

University of Southern Denmark, Graasten, Denmark<br />

1259. Pharmacokinetic-Pharmacodynamic Modeling of<br />

Ozoralizumab (ATN-103), a Novel Humanized Nanobody<br />

Tumor Necrosis Factor Inhibitor for Rheumatoid<br />

Arthritis. Chandrasekhar Udata 1 , Arnab Mukherjee 2 , Matt<br />

Hutmacher 3 , Mark Peterson 1 , Kai-Hsin Liao 1 , Tina Checchio 2 ,<br />

Kathy Shields 4 , Xu Meng 1 and Gail Comer 4 , 1 Pfizer, San<br />

Diego, CA, 2 Pfizer, Groton, CT, 3 A2PG, Ann Arbor, MI, 4 Pfizer,<br />

Collegeville, PA<br />

1260. Correlation of CDAI and SDAI with DAS in a Large Real-<br />

Life Cohort of Rheumatoid Arthritis Patients Treated with<br />

Infliximab. Denis Choquette 1 , William G. Bensen 2 , Milton<br />

F. Baker 3 , Sophie Elise Michaud 4 and Hayssam Khalil 5 ,<br />

1<br />

University of Montreal, Notre-dame Hospital, Montreal,<br />

QC, 2 McMaster University, Hamilton, ON, Hamilton, ON,<br />

3<br />

VIHA, Victoria, BC, 4 Merck Canada Inc, Montreal, QC,<br />

5<br />

Merck Canada Inc, Kirkland, QC<br />

1261. Development of a Whole Blood Assay to Determine<br />

Rituximab Mediated Complement Dependent Cytotoxicity<br />

of B Lymphocytes. Jonathan D. Jones 1 , B. JoNell Hamilton 2 ,<br />

Whitney Hilton 3 and William F. C. Rigby 4 , 1 Dartmouth-<br />

Hitchcock Medical Center, Lebanon, NH, 2 Dartmouth<br />

College, Lebanon, NH, 3 Dartmouth Hitchcock Med Ctr,<br />

Lebanon, NH, 4 Dartmouth-Hitchcock Med Ctr, Lebanon, NH<br />

1262. A Profile of Rheumatoid Arthritis Patients Treated with<br />

Tocilizumab in a United States Registry Population.<br />

Dimitrios A. Pappas 1 , Alan Rathbun 2 , George Reed 3 , Joel M.<br />

Kremer 4 , Isidro Villanueva 5 , Jenny Devenport 6 , Sarika Ogale 6 ,<br />

Ani John 6 and Jeffrey D. Greenberg 7 , 1 Columbia University,<br />

College of Physicians & Surge, New York, NY, 2 UMASS<br />

Medical School, Worcester, MA, 3 UMass Medical School,<br />

Worcester, MA, 4 Albany Medical College and The Center<br />

for Rheumatology, Albany, NY, 5 Viregen Macarena Hospital,<br />

Sevilla, Spain, 6 Genentech, South San Francisco, CA, 7 New<br />

York University School of Medicine, New York, NY<br />

1263. SNP Algorithms for Prediction of Efficacy and Adverse<br />

Events of Abatacept. Tsukasa Matsubara 1 , Satoru Koyano 2 ,<br />

Keiko Funahashi 2 , Takafumi Hagiwara 1 , Takako Miura 1 ,<br />

Kosuke Okuda 1 , Takeshi Nakamura 1 , Mitsuyoshi Iwahashi 3 ,<br />

Tomomi Tsuru 4 , Shoichi Uchimura 5 and Shigeru Honjo 6 ,<br />

1<br />

Matsubara Mayflower Hospital, Kato, Japan, 2 Research<br />

Institute of Joint Diseases, Kobe, Japan, 3 Higashi-Hiroshima<br />

Memorial Hospital, Higashi-hiroshima, Japan, 4 PS Clinic,<br />

Fukuoka, Japan, 5 Kanzaki Municipal General Hospital,<br />

Kanzaki, Japan, 6 Honjo Rheumatism Clinic, Takaoka, Japan<br />

1264. Low Persistence of Methotrexate Monotherapy in the<br />

Veterans Affairs Rheumatoid Arthritis (VARA) Registry.<br />

Grant W. Cannon 1 , Brian C. Sauer 1 , Katherine L. Martin 1 ,<br />

Candace L. Hayden 1 , Andreas M. Reimold 2 , Liron Caplan 3 ,<br />

J. Steuart Richards 4 , Gail S. Kerr 4 , Dannette S. Johnson 5<br />

and Ted R. Mikuls 6 , 1 Salt Lake City VA and University of<br />

Utah, Salt Lake City, UT, 2 Dallas VA and University of Texas<br />

Southwestern, Dallas, TX, 3 Denver VA and University of<br />

Colorado, Aurora, CO, 4 Washington DC VA and Georgetown<br />

University, Washington, DC, 5 Jackson VA and University of<br />

Mississippi Medical Center, Jackson, MS, 6 Omaha VA and<br />

University of Nebraska, Omaha, NE<br />

1265. Effects of TNF-Alpha Inhibitors on Lipid Profile and on Sub-<br />

Clinical Atherosclerosis in Rheumatoid Arthritis. Systematic<br />

Review and Meta-Analysis. Sylvain Mathieu 1 , Sarah<br />

Payet 1 , Bruno Pereira 2 , Eric Bruckert 3 and Martin Soubrier 2 ,<br />

1<br />

CHU Gabriel Montpied, Clermont-Ferrand, France, 2 CHU<br />

CLERMONT-FERRAND, Clermont-Ferrand, France, 3 CHU Pitié-<br />

Salpêtrière, AP–HP, Paris<br />

2011 <strong>Program</strong> <strong>Book</strong> 225

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