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Program Book - Confex

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Yasser M. El Miedany 1 , Maha El Gaafary 2 , Deborah Palmer 1 and<br />

Sally Youssef 2 , 1 Darent Valley Hospital, Dartford, United Kingdom,<br />

2<br />

Ain Shams University, Cairo, Egypt<br />

5:00 pm<br />

809. Ultrasonography Is a Potent Tool for Prediction of Ongoing<br />

Joint Destruction During Clinical Remission of Rheumatoid<br />

Arthritis<br />

Ryusuke Yoshimi, Kaoru Takase, Maasa Hama, Daiga Kishimoto,<br />

Kayo Terauchi, Reikou Watanabe, Takeaki Uehara, Darisuren<br />

Tsolmon, Sei Samukawa, Atsushi Ihata, Atsuhisa Ueda, Mitsuhiro<br />

Takeno and Yoshiaki Ishigatsubo, Yokohama City University<br />

Graduate School of Medicine, Yokohama, Japan<br />

and Center of Chronic Immunodeficiency, University of Freiburg,<br />

Freiburg, Germany, Freiburg, Germany, 4 Dept. of Rheumatology,<br />

Kantonsspital Aarau, Aarau, Switzerland, Aarau, Switzerland<br />

5:00 pm<br />

815. Synergistic TLR3 and TLR7 Activation by Endogenous<br />

Ligands Promotes Inflammatory Arthritis Through IRF5<br />

Pierre Duffau 1 , Tamar Aprahamian 1 , Hanni Menn-Josephy 1 ,<br />

Amanda Watkins 1 , Kei Yasuda 1 , Ramon G. Bonegio 1 , Paul A.<br />

Monach 2 , G. Kenneth Haines III 3 , Harris R. Perlman 4 , Christophe<br />

Richez5 and Ian Rifkin 1 , 1 Boston University School of Medicine,<br />

Boston, MA, 2 Boston University, Boston, MA, 3 Yale University,<br />

New Harven, CT, 4 Northwestern University, Chicago, IL, 5 France<br />

SUNDAY<br />

November 6, 2011<br />

46<br />

5:15 pm<br />

810. Does Rheumatoid Synovitis Activity Vary During the Day<br />

A Sonographic and Doppler Evaluation<br />

Agnes Lhoste, Bruno Pereira, Marion Couderc Sr. and Martin<br />

Soubrier, CHU CLERMONT-FERRAND, Clermont-Ferrand, France<br />

5:30 pm<br />

811. Sonoelastography Detects Rigidity of Salivary Glands in<br />

Primary Sjögren’s Syndrome<br />

Christian Dejaco 1 , Tobias DeZordo 2 , Daniel Heber 1 , Rainer Lipp 1 ,<br />

Andre Lutfi 1 , Marton Magyar 1 , Saelde Baumgartner 1 , Dorothea<br />

Zauner 1 , Winfried B. Graninger 1 and Josef Hermann 1 , 1 Medical<br />

University Graz, Graz, Austria, 2 Innsbruck Medical University,<br />

Innsbruck, Austria<br />

5:45 pm<br />

812. Vertebral Fracture Assessment (VFA): A Valid Tool to<br />

Detect Vertebral Fractures in Community-Dwelling Older<br />

Individuals.<br />

Diogo S. Domiciano 1 , Jaqueline B. Lopes 1 , Liliam Takayama 2 ,<br />

Camille Figueiredo 1 , Valéria Caparbo 1 , Eloisa Bonfa3 and Rosa<br />

M.R. Pereira 4 , 1 University of São Paulo, São Paulo, Brazil,<br />

2<br />

Faculdade de Medicina da Universidade de São Paulo, São<br />

Paulo, Brazil, 3 University of Sao Paulo, Sao Paulo, Brazil,<br />

4<br />

Disciplina de Reumatologia da FMUSP, Sao Paulo, Brazil<br />

W474a<br />

Innate Immunity and Rheumatic Disease<br />

Moderators: Richard M. Pope, MD; Northwestern University<br />

Medical School; Chicago, IL<br />

Susan A. Boackle, MD; University of Colorado Denver School of<br />

Medicine; Aurora, CO<br />

4:30 pm<br />

2011 Lee C. Howley, Sr. Prize for Arthritis Research Introductory<br />

Talk<br />

Speaker: Wayne M. Yokoyama, MD; Washington University<br />

School of Medicine; St. Louis, MO<br />

4:30 pm<br />

813. WITHDRAWN<br />

4:45 pm<br />

814. Circulating Mitochondrial DNA Copy Numbers As a Disease<br />

and Activity Marker in ANCA-Associated Vasculitis<br />

Ulrich A. Walker 1 , Nora M. Effelsberg 2 , Nils Venhoff 3 , Chingching<br />

Foocharoen 1 , Jens Thiel 3 , Paul Hasler 4 and Dirk Lebrecht 3 ,<br />

1<br />

University of Basel, Basel, Switzerland, 2 Dept. of Rheumatology<br />

and Centre of Chronic Immunodeficiency, University of Freiburg,<br />

Freiburg, Germany, Freiburg, Germany, 3 Dpt. of Rheumatology<br />

2011 <strong>Program</strong> <strong>Book</strong><br />

5:15 pm<br />

816. Soluble CD14 in Synovial Fluid From Patients with Early-<br />

Stage Osteoarthritis Augments Synoviocyte Responses to TLR-2<br />

and TLR-4 Ligands<br />

Anjali Nair 1 , Veero Kanda 1 , Charles Bush-Joseph 1 , Nikhil Verma 1 ,<br />

Susanna Chubinskaya 1 , Katalin Mikecz 1 , Tibor T. Glant 1 , Anne-<br />

Marie Malfait 1 , Mary K. Crow 2 , Greg Spear 1 , Alison Finnegan1<br />

and Carla R. Scanzello 1 , 1 Rush University Medical Center,<br />

Chicago, IL, 2 Hospital for Special Surgery, New York, NY<br />

5:30 pm<br />

817. Abatacept (CTLA-4Ig) Treatment Reduces Adhesion and<br />

Migratory Capacity of Monocytes in Patients with Rheumatoid<br />

Arthritis (RA)<br />

Michael Bonelli 1 , Elisabeth Ferner 1 , Anastasiya Hladik 1 , Lisa<br />

Goeschl 1 , Thomas Karonitsch 1 , Hans Peter Kiener 1 , Stefan<br />

Blueml 1 , Carl-Walter Steiner 1 , Michael Bergmann 1 , Josef Smolen 2<br />

and Clemens Scheinecker 1 , 1 Medical University of Vienna,<br />

Vienna, Austria, 2 Medical University of Vienna and Hietzing<br />

Hospital, Vienna, Austria<br />

5:45 pm<br />

818. A Novel Autoinflammatory Syndrome Presenting with<br />

Chronic Atypical Neutrophilic Dermatitis, Lipodystrophy<br />

and Elevated Temperatures (CANDLE syndrome) Caused by<br />

Mutation in the Immunoproteasome<br />

Yin Liu 1 , Yongqing Chen 1 , Yuval Ramot 2 , Damaris Garcia 1 , Antonio<br />

Torrelo 3 , Afzal Sheikh 4 , Amy Paller 5 , Adam Reinhardt 6 , Deborah<br />

Stone 1 , Massimo Gadina 7 , Plass1 Plass 1 , Dawn Chapelle 1 ,<br />

Zlotogorski Zlotogorski 2 and Raphaela T. Goldbach-Mansky 8 ,<br />

1<br />

Translational Autoinflammatory Disease Section, Office of<br />

the Clinical Director NIAMS, Bethesda, MD, 2 Department of<br />

Dermatology, Hadassah-Hebrew University Medical Center,<br />

Jerusalem, Israel., Jerusalem, Israel, 3 Departments of Pediatric<br />

Dermatology, Hospital Niño Jesús, Madrid, Spain, Madrid, Spain,<br />

4<br />

Medical Genetics Branch, NHGRI, Bethesda, MD, 5 Departments<br />

of Dermatology and Pediatrics, Feinberg School of Medicine,<br />

Northwestern University, Chicago, IL, USA;, Chicago, IL, 6 Faculty<br />

of Physicians of the University of Nebraska Medical Center,<br />

College of Medicine, Nebraska, 7 NIAMS, Bethesda, MD, 8 NIH,<br />

Bethesda, MD<br />

W471b<br />

Muscle Biology, Myositis and Myopathies: Insights into<br />

the Pathogenesis of Myositis<br />

Moderators: Jiri Vencovsky, MD, PhD; Institute of<br />

Rheumatology; Prague, Czech Republic<br />

Lucy R. Wedderburn, MD, PhD; University College London;<br />

London, United Kingdom

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