Program Book - Confex

ACR/ARHP Poster Session C
Joana Caetano-Lopes 2 , Ana Lopes 3 , Ana Catarina Vale 4 ,
Inês Aleixo 3 , Inês P. Perpétuo 2 , Ana Sofia Pena 3 , Alexandra
Faustino 3 , Alexandre Sepriano 3 , Joaquim Polido-Pereira 5 ,
Elsa Vieira-Sousa 6 , Bruno Vidal 7 , JC Romeu 8 , PM Amaral 4 ,
Luis G. Rosa 4 , José A. Pereira da Silva 9 , Jacinto Monteiro 10 ,
Maria Fátima Vaz 4 , J. E. Fonseca 5 and Helena Canhão 5 ,
1
Rheumatology Research Unit, Instituto de Medicina
Molecular, Faculdade de Medicina da Universidade de
Lisboa and Rheumatology Department, Centro Hospitalar de
Lisboa Norte, EPE, Hospital de Santa Maria, Lisbon, Portugal,
2
Rheumatology Research Unit, Faculdade de Medicina da
Universidade de Lisboa, Lisbon, Portugal, 3 Rheumatology
Research Unit, Instituto de Medicina Molecular, Faculdade
de Medicina da Universidade de Lisboa, Lisbon, Portugal,
4
Department of Mechanical Engineering, Instituto Superior
Técnico, ICEMS, Lisbon, Portugal, 5 Instituto de Medicina
Molecular, Faculdade de Medicina da Universidade de
Lisboa and Rheumatology Department, Centro Hospitalar
de Lisboa Norte, EPE, Hospital de Santa Maria, Lisboa,
Portugal, 6 Instituto de Medicina Molecular, Faculdade de
Medicina da Universidade de Lisboa, Lisbon, Portugal,
7
Instituto de Medicina Molecular, Faculdade de Medicina da
Universidade de Lisboa, Lisbon, Portugal., Lisbon, Portugal,
8
Hospital de Santa Maria, Lisbon, Portugal, 9 Rheumatology
Department, Centro Hospitalar de Lisboa Norte, EPE,
Hospital de Santa Maria, Lisbon, Portugal, 10 Orthopaedics
Department, Hospital de Santa Maria, Lisbon, Portugal
1793. Alarmins s100a8 and s100a9 Elicit a Higher Catabolic
Response in Osteoarthritic Chondrocytes Compared
to Normal Chondrocytes That Is Toll Like Receptor 4
Dependent. Rik Schelbergen 1 , Arjen B. Blom 1 , Martijn H.J.
van den Bosch 1 , Annet Sloetjes 1 , Thomas Vogl 2 , Johannes
Roth 2 , Wim B. van den Berg 1 and Peter L.E.M. van Lent 1 ,
1
Radboud University Nijmegen Medical Centre, Nijmegen,
Netherlands, 2 University of Muenster, Munster, Germany
1794. Periostin, An Osteoblast Stimulating Factor, Regulates
Cartilage Metabolism Via MMP-13 Activation. Mukundan
Attur 1 , Glyn Palmer 1 , Yuki Tachida 2 , Seiichiro Kumakura 2 ,
Kohei Shimada 2 and Steven B. Abramson 1 , 1 NYU Hospital
for Joint Diseases, New York, NY, 2 Daiichi-Sankyo Co. Ltd.,,
Tokyo, Japan
1795. Sirt1 Deficient Mice Exhibit An Altered Cartilage
Phenotype. Odile H. Gabay Engel 1 , Christelle Sanchez 2 ,
Mona dvir-Ginzberg 3 , Viktoria Gagarina 1 , Eun Jin Lee 1 ,
Kristien J. Zaal 1 , Michael McBurney 4 and David J. Hall 1 ,
1
NIH, Bethesda, MD, 2 Bone and Cartilage Research Unit,
Liege, Belgium, 3 Hebrew University- Hadassah Ein Kerem,
Jerusalem, Israel, 4 Ottawa Hospital, Ottawa, ON
1796. Rac1 and NADPH Oxidase Regulate NFκB Activity and
MMP-13 Expression in Chondrocytes in Response to
Integrin Activation. Richard F. Loeser, Elizabeth A. Erickson
and David A. Long, Wake Forest University, Winston-Salem,
NC
1797. Disease-Specific Induction of Fibroblast Activation
Protein Alpha in Rheumatoid Arthritis. Christina Wunrau 1 ,
Marianne Heitzmann 1 , Corinna Wehmeyer 1 , George Kollias 2 ,
Thomas Pap 1 and Berno Dankbar 1 , 1 University Hospital
Muenster, Muenster, Germany, 2 Biomedical Sciences
Research Center ‘Alexander Fleming’, Vari, Greece
1798. Theragnostic Nanosomes for Detection and Treatment of
Early Osteoarthritis and Cartilage Damage. Karen A. Hasty 1 ,
Hongsik Cho 2 , Eugene Pinkhassik 3 and John M. Stuart 4 ,
1
University of Tennessee Health Science Center, VA Medical
Center, Memphis, TN, 2 University of Tennessee Health
Science Center, Memphis, TN, 3 University of Memphis,
Memphis, TN, 4 VA Medical Center, University of Tennessee
Health Science Center, Memphis, TN
1799. Sclerostin Levels in RA and Its Relationship to Disease
Activity and Radiographic Joint Damage. M. Vis 1 , K.
Britsemmer 2 , A.C. Heijboer 1 , N. Bravenboer 1 , D. van
Schaardenburg 2 and W. F. Lems 1 , 1 VU University medical
center, Amsterdam, Netherlands, 2 Jan van Breemen
Research Institute / Reade, Amsterdam, Netherlands
1800. A Novel Method of Basic Calcium Phosphate Crystal
Quantification in Synovial Fluid Using a Tetracycline
Binding Assay. Jonathan Kushi 1 , Claudia Gohr 1 , Brian
Jubeck 1 , Peter A. Simkin 2 and Ann K. Rosenthal 1 , 1 Medical
College of Wisconsin, Milwaukee, WI, 2 University of
Washington, Seattle, WA
1801. Revisiting Chemical and Morphological Diversity of
Calcium-Containing Crystals in Human Osteoarthritic
Menisci. Christelle Nguyen 1 , Frédéric Lioté 1 , Didier
Hannouche 2 , Valérie Bousson 3 , Frédéric Velard 1 , Michel
Daudon 4 , Dominique Bazin 5 and Hang-Korng Ea 1 , 1 UMR-S
60 6 , INSERM & Paris Diderot University; PRES Sorbonne
Paris-Cité; Lariboisière Hospital, Paris, France, 2 Orthopaedic
Surgery Department; Lariboisière Hospital (AP-HP); Univ.
Paris Diderot, Sorbonne Paris-Cité, Paris, France, 3 Radiology
Department; Lariboisière Hospital (AP-HP); University Paris
Diderot, Paris, France, 4 Service de Biochimie A; Necker
Hospital (AP-HP), Paris, France, 5 Laboratoire de Physique des
Solides; Paris Sud University, Orsay, France
1802. Inhibition of p38 Signaling Negatively Affects
Chondrogenesis in Vitro, but Does Not Inhibit Ankylosis in
a Model of Ankylosing Spondylitis. Kirsten Braem, Frank P.
Luyten and Rik Lories, KU Leuven, Leuven, Belgium
1803. Human Chondrocyte Behaviour During In Vitro
Over Expression of Normal and Mutated HFE, the
Hemochromatosis Gene. Vanessa Martelli 1 , John A. Di
Battista 1 , Pantelis Panopalis 1 , John Antoniou 2 , Michael
Sebag 1 , Brian Gilfix 1 and Henri A. Ménard 1 , 1 McGill
University Health Center, Montreal, QC, 2 Jewish General
Hospital, Montreal, QC
1804. Blockade of Delta-like1 Suppresses Osteoclastgenesis
and Arthritis. Chiyoko Sekine 1 , Akemi Koyanagi 1 , Noriko
Koyama 1 , Katsuto Hozumi 2 , Shigeru Chiba 3 and Hideo Yagita 1 ,
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