Program Book - Confex

Berlin, Germany, 2 Charité - Universitätsmedizin Berlin, Berlin,
Germany
5:30 pm
841. Gene-Gene Interactions in Folate Pathway Contribute to
Methotrexate Adverse Events in Rheumatoid Arthritis
Thierry Dervieux 1 , Judith Wessels 2 , J. M. Kremer 3 , Tom W.J.
Huizinga 2 and Henk-Jan Guchelaar 2 , 1 Exagen Diagnostics,
Albuquerque, NM, 2 Leiden University Medical Center, Leiden,
Netherlands, 3 Albany Medical College and The Center for
Rheumatology, Albany, NY
5:45 pm
842. Patterns of Interaction Between Genetic and Non-Genetic
Attributes and Methotrexate Efficacy in Rheumatoid Arthritis
Thierry Dervieux 1 , Judith Wessels 2 , J. M. Kremer 3 , Leonid
Padyukov 4 , Maria Seddighzadeh 4 , Saedis Saevarsdottir 4 , R.F.
van Vollenhoven 4 , Lars Klareskog 4 , T. Huizinga 2 and Henk-Jan
Guchelaar 2 , 1 Exagen Diagnostics, Albuquerque, NM, 2 Leiden
University Medical Center, Leiden, Netherlands, 3 Albany
Medical College and The Center for Rheumatology, Albany, NY,
4
Karolinska Institutet, Stockholm, Sweden
W192b
Systemic Sclerosis Fibrosing Syndromes and Raynaud’s
– Clinical Aspects and Therapeutics I
Moderators: Maureen D. Mayes, MD, MPH; University of Texas
Health Science Center at Houston; Houston, TX
Jessica K. Gordon, MD; Hospital for Special Surgery; New York,
NY
4:30 pm
843. Survival and Predictors of Mortality In Australian Patients
with Connective Tissue Disease-Associated Pulmonary Arterial
Hypertension
Gene-Siew Ngian 1 , Wendy Stevens 2 , Jill Byron 2 , Ai Tran 3 , Janet E.
Roddy 3 , Robert Minson 4 , Catherine L. Hill 5 , Ken Chow 6 , Joanne
Sahhar 7 , Susanna Proudman 6 and Mandana Nikpour 1 , 1 The
University of Melbourne, Melbourne, Australia, 2 St Vincent’s
Hospital, Melbourne, Australia, 3 Royal Perth Hospital, Perth,
Australia, 4 Flinders Medical Centre, Adelaide, Australia, 5 The
Queen Elizabeth Hospital, Woodville, Australia, 6 Royal Adelaide
Hospital, Adelaide, Australia, 7 Monash Medical Centre,
Melbourne, Australia
4:45 pm
844. Prognostic and Diagnostic Significance of Autoantibodies
to Citrullinated Proteins (ACPA) in Patients with a Scleroderma-
Rheumatoid Arthritis (SSc-RA) Overlap Syndrome
Makoto Soejima 1 , Zhou Zhijie 2 , Donald M. Jones 1 , Danielle
Goudea u 1 , Christine L. Amity 1 , Lynne M. Frydrych 1 , Robyn T.
Domsic 1 , Aarat M. Patel 1 , Larry W. Moreland 3 , David M. Lee 4 ,
Thomas A. Medsger 1 and Marc C. Levesque 1 , 1 Univ of Pittsburgh
Med Ctr, Pittsburgh, PA, 2 Aurora Health Care Oshkosh, Oshkosh,
WI, 3 University of Pittsburgh, Pittsburgh, PA, 4 Brigham and
Womens Hospital, Boston, MA
5:00 pm
845. Detection of Autoantibodies to RNA-Protein Complex in
Scleroderma by Quantitative-PCR of RNA Components of the
Antigens
Angela Ceribelli, Minoru Satoh and Edward K.L. Chan, University
of Florida, Gainesville, FL
5:15 pm
846. The Significance of Tendon Friction Rubs in Early Diffuse
Systemic Sclerosis Patients
Adam Doré 1 , Thomas A. Medsger Jr. 2 , Mary Lucas 3 , Dana Ivanco 3
and Robyn T. Domsic 2 , 1 UPMC Presbyterian Shadyside Hospital,
Pittsburgh, PA, 2 University of Pittsburgh Med Ctr, Pittsburgh, PA,
3
University of Pittsburgh, Pittsburgh, PA
5:30 pm
847. Long-Term Follow-up of Limited Cutaneous Systemic
Sclerosis Patients with Anti-Th/to Antibody
Erin Snell 1 , Mary Lucas 1 , Dana Ivanco 1 , Thomas A. Medsger 2 and
Robyn T. Domsic 1 , 1 University of Pittsburgh, Pittsburgh, PA, 2 Univ
of Pittsburgh, Pittsburgh, PA
5:45 pm
848. A Prospective Observational Study of Mycophenolate
Mofetil Treatment in Rapidly Progressive Diffuse Cutaneous
Systemic Sclerosis of Recent Onset
Fabian A. Mendoza 1 , Sarah J. Nagle 2 , Jason B. Lee3 and Sergio
A. Jimenez 4 , 1 Jefferson Institute of Molecular Medicine and
Scleroderma Center, Rheumatology Division, Department
of Medicine, Thomas Jefferson University, Philadelphia, PA,
2
Jefferson Medical College, Thomas Jefferson University,
Philadelphia, PA, 3 Dermopathology Division, Department
of Dermatology and Cutaneous Biology, Thomas Jefferson
University, Philadelphia, PA, 4 Jefferson Institute of Molecular
Medicine, Thomas Jefferson University, Philadelphia, PA
W193a
T-cell Biology and Targets in Autoimmune Disease:
Lymphocyte Biology and Targets in Autoimmune
Disease
Moderators: Joseph Holoshitz, MD; University of Michigan; Ann
Arbor, MI
Sujata Sarkar, MD; University of Arizona; Tucson, AZ
4:30 pm
849. Therapeutic Effects of TGF-β-Induced Regulatory T Cells on
the Established Autoimmune Diseases
Song G. Zheng 1 , Qin Lan 2 , Julie Wang 2 , David Brand 3 , David A.
Horwitz 4 , Zhong-Min Liu 5 and Hejian Zou 6 , 1 USC Keck School of
Medicine, Los Angeles, CA, 2 University of Southern California,
Los Angeles, CA, 3 VA Medical Center, Memphis, TN, 4 USC School
of Medicine, Los Angeles, CA, 5 Shanghai East Hospital, Tonji
University, Shanghai, China, 6 Huashan Hospital, Shanghai, China
4:45 pm
850. p53 Regulates Th17-Mediated Autoimmune Arthritis
Jin-Sil Park 1 , Mi-La Cho 1 , Mi-Ae Lim 1 , Young-Mee Moon 1 , Hye-
Jwa Oh 1 , Joo-Yeon Jhun 1 , Jun-Geol Ryu 1 , Jae-Kyeong Byun 1 ,
Eun-Joo Jeon 1 , Hye-Rin Jeong 1 , Sang-Heon Lee 2 and Ho-Youn
Kim 1 , 1 Catholic University of Korea, Seoul, South Korea, 2 Konkuk
University School of Medicine, Seoul, South Korea
5:00 pm
851. Citrullinated Fibrinogen-Specific CD4+ T Cells Display
Memory and Regulatory Phenotypes
Laura Su and Mark M. Davis, Stanford University School of
Medicine, Stanford, CA
SUNDAY
November 6, 2011
2011 Program Book 49