Program Book - Confex

TUESDAY
November 8, 2011
9:25 am
Is Methotrexate a Disease Modifying Agent in Psoriatic
Arthritis
Gabrielle H. Kingsley, MBChB, PhD; Kings College London;
London, United Kingdom
9:50 am
Reactive Arthritis: Clinical Insights and Treatment Options
John D. Carter, MD; University of South Florida; Tampa, FL
Upon completion of this session, participants should be able to:
• outline the impact of tumor necrosis factor inhibition on
the progression of vertebral changes observed on magnetic
resonance imaging in antiphospholipid syndrome patients
• discuss new treatment approaches to the prevention of
pathologic new bone formation in antiphospholipid syndrome
• review the data on the efficacy and safety of methotrexate in
prostate-specific antigen
• assess if methotrexate is a disease-modifying anti-rheumatic
drugs in prostate-specific antigen
• state the strains of chlamydia associated with reactive arthritis
• summarize the recent evidence regarding the efficacy and
safety of prolonged antibiotic therapy for reactive arthritis
induced by chlamydia
ACR IMMUNOLOGY UPDATES FOR THE
CLINICIANS
9:00 - 10:00 am
W375c
Genetic Defects, AIRE and Autoimmunity c/r
Moderator: Gregg J. Silverman, MD; New York University School
of Medicine; New York, NY
Speaker: Mark Anderson, MD, PhD; University of California, San
Francisco; San Francisco, CA
Upon completion of this session, participants should be able to:
• describe basic principles of T cell biology and selection of
antigen specific responses
• evaluate how expression of self antigens in the thymus
is controlled and under the regulation of certain genetic
elements
• cite how impaired expression of genes such as autoimmune
regulator can result in organ specific autoimmunity, and how
this has changed our understanding of autoimmune disease
pathogenesis
ACR STATE-OF-THE-ART LECTURES
9:00 - 10:00 am
W183a
Cytokine and Chemokine Regulation of Chronic Pain
R
Moderator: Anne-Marie Malfait, MD, PhD; Rush University
Medical Center; Chicago, IL
Speaker: Richard J. Miller, PhD; Northwestern University;
Evaston, IL
Upon completion of this session, participants should be able to:
• describe how the expression of inflammatory cytokines in
association with tissue damage triggers diverse changes in the
behavior of sensory neurons in the context of chronic pain
syndromes
• summarize the actions of inflammatory cytokines synthesized
by dorsal root ganglia neurons, associated glial cells, as well as
by astrocytes and microglia in the spinal cord
• translate the knowledge of mechanisms of chronic pain
generation into novel analgesic targets
W375a
Neutrophil Recruitment by Intravascular Danger
Signals R
Moderator: Christopher T. Ritchlin, MD, MPH; University of
Rochester Medical Center; Rochester, NY
Speaker: Paul Kubes, PhD; University of Calgary; Calgary, AB,
Canada
Upon completion of this session, participants should be able to:
• define the term damage associated molecular patterns and
how these molecules participate in the inflammatory response
• list the molecular signals that direct neutrophil migration
• describe the multistep cascade that allows neutrophils to
sense and home to sites of sterile inflammation
ACR/ARHP POSTER SESSION C AND
POSTER TOURS
9:00 am - 6:00 pm
Poster presenters will be available from 9:00 - 11:00 am
(abstracts # 1733 - 2426). Poster tours will be held 9:00 - 9:45
amand 10:15 - 11:00 am. Morning snacks will be available from
9:00 - 10:30 am.
Guided Poster Tours
HALL F2 - Poster Hall
Guided poster tours allow scientific attendees to ask questions
and gain insights from some of the best-known rheumatology
leaders. Tours are complimentary; however, registration is
required and is limited to scientific attendees. If you preregistered
for a tour, you should have received a ticket with your
meeting materials. Once you have your ticket, check in at the
tour desk 15 minutes prior to the start of your tour to receive
your headset. Your reservation will be held only until 5 minutes
prior to the start of the tour. After this time, your reservation is
not guaranteed and may be released to standby attendees. If you
did not pre-register, tickets may be available in the registration
area (Hall F2 Entrance). Alternatively, you may go directly
to the poster tour desk and wait for a standy ticket. Standby
tickets will be assisgned on a first-come, first served basis 5
minutes prior to the start of each tour. Each tour participant will
receive a wireless headset which will be registered against the
participants’ registration ID. Participants will be charged $50 if
the headset is not returned within 15 minutes of the end of the
tour.
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2011 Program Book