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***<br />
THE DISEASES − CHAPTER 4<br />
145<br />
Investment targets for preventive chemotherapy against onchocerciasis and<br />
lymphatic filariasis in Africa (delivery excluding medicines), 2015–2030<br />
80<br />
60<br />
Constant US$ millions<br />
40<br />
20<br />
●<br />
0<br />
2015<br />
2020<br />
Year<br />
2025<br />
2030<br />
Notes: Shaded areas reflect the range determined by low and high values of the unit cost benchmarks; they do<br />
not reflect uncertainty about future rates of scale-up and scale-down of interventions. The dots in 2012 are actual<br />
numbers reported (when available) multiplied by the unit cost benchmarks; these are not actual expenditures, but<br />
can be thought of as a benchmark for actual expenditures. All numbers expressed in US$ are constant (real) US$,<br />
adjusted to reflect purchasing power in the United States of America in 2015.<br />
available evidence suggests that mass treatment can be stopped. The investment target<br />
for the delivery of preventive chemotherapy (excluding medicines) during 2015–2020 is<br />
about US$ 58 million (US$ 45–73 million) per year, falling to US$ 4.1 million (US$ 2.7–5.6<br />
million) per year during 2021–2030.<br />
Chapter 2 discusses the need for post-preventive chemotherapy surveillance and<br />
management of morbidity and disability prevention.<br />
_____________________<br />
1<br />
Keating J, Yukich JO, Mollenkopf S, Tediosi F. Lymphatic filariasis and onchocerciasis prevention, treatment, and control<br />
costs across diverse settings: a systematic review. Acta Trop. 2014;135:86–95. doi:10.1016/j.actatropica.2014.03.017.<br />
2<br />
Coffeng LE, Stolk WA, Zouré HGM, Veerman JL, Agblewonu KB, Murdoch ME et al. African Programme for<br />
Onchocerciasis Control 1995–2015: model-estimated health impact and cost. PLoS Negl Trop Dis. 2013;7:e2032.<br />
doi:10.1371/journal.pntd.0002032.<br />
3<br />
Coffeng LE, Stolk WA, Zouré HGM, Veerman JL, Agblewonu KB, Murdoch ME et al. African programme for onchocerciasis<br />
control 1995–2015: updated health impact estimates based on new disability weights. PLoS Negl Trop Dis. 2014;8:e2759.<br />
doi:10.1371/journal.pntd.0002759.