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22 THIRD WHO REPORT ON NEGLECTED TROPICAL DISEASES<br />
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spraying are targeted for areas of South-East Asia in which malaria programmes are not<br />
already active – areas with a population of about 35 million people in 2015. This report does<br />
not yet include targets for vector control against lymphatic filariasis, although integrated<br />
vector management is promoted to support the elimination strategy.<br />
Population targets for surveillance after preventive chemotherapy has been stopped are<br />
based on the administration of three surveys within 3–6 years of stopping the intervention<br />
for lymphatic filariasis, onchocerciasis or trachoma.<br />
Populations targeted for coverage with treatment and care<br />
For the purposes of this chapter, population targets for coverage with treatment and<br />
care are based on the historic relationship between notification rates and GDP per capita.<br />
Fig. 2.3 displays targets for the number of people targeted for coverage, including financial<br />
protection. These targets aim to prevent death and disability as well as indebtedness and<br />
impoverishment among the more than 500 000 households still affected by Buruli ulcer,<br />
human African trypanosomiasis, the leishmaniases and leprosy each year.<br />
If expressed relative to the total populations within endemic countries, these targets<br />
imply that by 2020, incidence would be less than 1 per 10 000 people for leprosy, gambiense<br />
human African trypanosomiasis and visceral leishmaniasis. It is difficult to set population<br />
targets for Buruli ulcer given the extent of under-reporting and unexplained year-over-year<br />
fluctuations in the number of cases reported – the targets displayed in Fig. 2.3 (panel A) are<br />
effectively flat over time. The number of people targeted for coverage by treatment and care<br />
of gambiense human African trypanosomiasis in 2030 exceeds a recently set target for zero<br />
incidence, but is consistent with the expectation that coverage will need to be maintained<br />
during confirmation of the interruption of transmission.<br />
Population targets for active case-finding for Buruli ulcer and leprosy are based on the<br />
population targets for treatment and care and targets for the number of contacts to be<br />
traced. Active case-finding for human African trypanosomiasis is based on populations<br />
living in high and very high risk areas targeted for annual mobile teams and on moderate<br />
risk areas targeted for 3-yearly mobile teams. Camp-based or house-to-house screening for<br />
visceral leishmaniasis is limited to parts of Bangladesh and India. Assumptions behind the<br />
targets for morbidity management and disability prevention are available from the technical<br />
appendix. 1<br />
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1<br />
The technical appendix and related code using the free software R will also be made available via http://www.who.int/<br />
neglected_diseases/en/