Hap Map Project - Bgbunict.it

More documents

Recommendations

Info

The coinher<strong>it</strong>ance of SNP alleles on these haplotypes leads to associations between these alleles in the population (known as linkage disequilibrium, LD)
Linkage disequilibrium S<strong>it</strong>uation in which some combinations of alleles or genetic markers occur more or less frequently in a population than would be expected from a random formation of haplotypes from alleles based on their frequencies. Non-random associations between polymorphisms at different loci are measured by the degree of linkage disequilibrium (LD).
Page 1 and 2: The International HapMap Project An
Page 3 and 4: Genetic and environmental contribut
Page 5 and 6: Discovering these genetic factors w
Page 7 and 8: Human Genetic Variations Primarily
Page 9 and 10: SNPs Sites in the genome where the
Page 11 and 12: Polymorphism A sequence variation t
Page 13 and 14: In principle, SNPs could be bi-, tr
Page 15 and 16: Non-coding SNPs Example: Regulatory
Page 17 and 18: Coding SNPs Example: Non-synonymous
Page 19: A particular combination of alleles
Page 23 and 24: Many empirical studies have shown h
Page 25: The International HapMap Project is
Page 28 and 29: The HapMap was designed to determin
Page 30 and 31: The International HapMap Consortium
Page 32 and 33: The project had become practical by
Page 34 and 35: The Phase I HapMap Phase I of the H
Page 36 and 37: To study patterns of genetic variat
Page 38 and 39: They estimate that genotypes relate
Page 40 and 41: Genotyping in phase II was attempte
Page 42 and 43: Variation in SNP density within the
Page 44 and 45: Studies in additional populations h
Page 46 and 47: APPLICATION OF THE HAPMAP TO COMMON
Page 48 and 49: The history of high-density GWA sca
Page 50 and 51: A genome-wide association study ide
Page 52 and 53: Beyond SNPs: Copy Number Variants a
Page 54 and 55: Although not as common as SNPs, the
Page 56 and 57: In 2004, the interrogation of genom
Page 58 and 59: It is now recognized that the genom
Page 60: Bibliografia The International HapM

Hap Map Project - Bgbunict.it

Create successful ePaper yourself

Delete template?

Save as template?