Hap Map Project - Bgbunict.it
Hap Map Project - Bgbunict.it
Hap Map Project - Bgbunict.it
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They estimate that genotypes related to just five variants in three different genes can<br />
explain 50% of the risk of developing AMD<br />
The new genetic common variant identified was found in a non-coding region of the<br />
Complement Factor H (CFH) gene, other variants of which were recently shown to<br />
be associated w<strong>it</strong>h the risk of developing AMD.<br />
In add<strong>it</strong>ion to CFH on chromosome 1<br />
the complement factor B (BF) gene on chromosome 6<br />
complement component 2 (C2) gene on chromosome 6<br />
a common variant (A69S) is in hypothetical gene LOC387715 on chromosome 10.<br />
Interestingly, these three genes do not appear to interact directly, but instead<br />
contribute to the risk of AMD independently.
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